A0A954ZYD3 · A0A954ZYD3_9BACT
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids919 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- diphosphate + H2O + Na+(in) = H+ + Na+(out) + 2 phosphate
CHEBI:33019 + CHEBI:15377 + Na+ (in)CHEBI:29101= CHEBI:15378 + Na+ (out)CHEBI:29101+ 2 CHEBI:43474
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 512 | Determinant of potassium dependence | ||||
Sequence: A |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Planctomycetota > Phycisphaerae > Phycisphaerales
Accessions
- Primary accessionA0A954ZYD3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 23-41 | Helical | ||||
Sequence: LYWLAPVGGLCALAMAFFF | ||||||
Transmembrane | 76-94 | Helical | ||||
Sequence: VVAGVFVLLVAFLGIMYAL | ||||||
Transmembrane | 100-123 | Helical | ||||
Sequence: LSMIGVPVAGFLSGLCGWFGMRMA | ||||||
Transmembrane | 144-169 | Helical | ||||
Sequence: VAFRSGAVMGLNVVGFAILDVSFWFF | ||||||
Transmembrane | 181-201 | Helical | ||||
Sequence: LQIITTVMLSFGMGASTQALF | ||||||
Transmembrane | 260-278 | Helical | ||||
Sequence: YYGSILATIALGAAAAYTM | ||||||
Transmembrane | 284-311 | Helical | ||||
Sequence: ALALAFMLVVAPMALAGAGILCSIFGIF | ||||||
Transmembrane | 332-351 | Helical | ||||
Sequence: VWLASAAIIVVSALLLYFLF | ||||||
Transmembrane | 371-392 | Helical | ||||
Sequence: LWLSILSGLIAGNVIAYATEYY | ||||||
Transmembrane | 427-446 | Helical | ||||
Sequence: WASLVVVVVAIITAFTFAGG | ||||||
Transmembrane | 452-473 | Helical | ||||
Sequence: MGLYGVGIAAVGMLSTLGITLA | ||||||
Transmembrane | 517-535 | Helical | ||||
Sequence: GFAIGSAALTALALFAAYI | ||||||
Transmembrane | 667-689 | Helical | ||||
Sequence: VLGGIFMGALLAFLFCAMTMNAV | ||||||
Transmembrane | 757-777 | Helical | ||||
Sequence: MVLPSLLAILVPIGVGLVLGV | ||||||
Transmembrane | 783-805 | Helical | ||||
Sequence: LLAGGLTCGFAVAVFMANAGGAW | ||||||
Transmembrane | 889-909 | Helical | ||||
Sequence: ILIKLISIVSVVFAGLIVKFS |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length919
- Mass (Da)96,032
- Last updated2023-02-22 v1
- Checksum8FA668C32EAF3040