A0A954TVP5 · A0A954TVP5_9BACT

  • Protein
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • Gene
    hppA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Requires K+ for maximal activity.

Features

Showing features for site.

TypeIDPosition(s)Description
Site509Determinant of potassium dependence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding
Molecular Functionpotassium ion binding
Biological Processsodium ion transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Putative K(+)-stimulated pyrophosphate-energized sodium pump
  • EC number
  • Alternative names
    • Membrane-bound sodium-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (Na(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      KDB05_13875

Organism names

Accessions

  • Primary accession
    A0A954TVP5

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-26Helical
Transmembrane60-79Helical
Transmembrane85-105Helical
Transmembrane135-159Helical
Transmembrane171-191Helical
Transmembrane250-270Helical
Transmembrane290-311Helical
Transmembrane332-349Helical
Transmembrane355-377Helical
Transmembrane418-439Helical
Transmembrane445-470Helical
Transmembrane514-532Helical
Transmembrane647-666Helical
Transmembrane714-732Helical
Transmembrane738-758Helical
Transmembrane805-826Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    832
  • Mass (Da)
    86,946
  • Last updated
    2023-02-22 v1
  • Checksum
    A18C83D18406EB36
MDTTLIVWGLAFTASVVALVQAFLFYKSMMAADEGNARMVEIAGYVREGANAYLKQQYKVVGVFFVVIVILLSIAAFVLKVQSEFVPFAFLTGGFFSGLAGWFGMKTATWASSRTAAGAQKSLNQGLQVAFRSGAVMGLTVVGLGLIDITVWFGFLYYVWPNVLGFEALSLIDITVTMLCFGMGASAQALFARVGGGIFTKAADVGADLVGKVEQGIPEDDPRNPATIADNVGDNVGDVAGMGADLYESYCGSILATAALGVAAFASGSLVATDRAGMELPSEAAQLQALLLPMAIAGVGIFLSIIGIYLVRTNDDATQKNLLSALARGIDASTILVVVAAAGLSWWLMPRVDGTLIFGIPGVAFSIVVGLASGWLIGKWTEYATSDEYAPTKNLAEQAETGPATLIIGGIADGMMSVWVPVLVVCAATLLAFGCAAGWNFADVSYFALGLYGVGIAAVGMLSTLGITLATDAYGPIADNAGGNAEMAHLDPIVRQRTDALDSLGNTTAATGKGFAIGSAALTALALLAAYIEEVRVGFERWGNEIVATQSADGIYKASTGFVIEKHGDHAHLYLAMPNDVRHPDIKSSWDAIGRDQWPAKVDDSLFDQSTHGELRFRSGGRLVDVHSATLPDFTTYYDASLMNPKVLVGVFLGAMATFVFCAMTMKAVGRAAKGMVEEVRRQFREKPGIMKGTDLPDYAAPVAISTKAAQREMVVPSLLGLVTPLAVGLLLGVGGVLGLLVGTLTCGFCVAIFMANAGGSWDNAKKYIEAGHHGGKGSVAHKAGVVGDTVGDPFKDTSGPSLNILIKLMSMVSVVVAGLVVRYSLMAMGVF

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAGQPM010000099
EMBL· GenBank· DDBJ
MCA9143879.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp