A0A954TVP5 · A0A954TVP5_9BACT
- ProteinPutative K(+)-stimulated pyrophosphate-energized sodium pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids832 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na+ movement across the membrane.
Catalytic activity
- diphosphate + H2O + Na+(in) = H+ + Na+(out) + 2 phosphate
CHEBI:33019 + CHEBI:15377 + Na+ (in)CHEBI:29101= CHEBI:15378 + Na+ (out)CHEBI:29101+ 2 CHEBI:43474
Cofactor
Activity regulation
Requires K+ for maximal activity.
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 509 | Determinant of potassium dependence | ||||
Sequence: A |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | potassium ion binding | |
Biological Process | sodium ion transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative K(+)-stimulated pyrophosphate-energized sodium pump
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Planctomycetota > Planctomycetia > Planctomycetales
Accessions
- Primary accessionA0A954TVP5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-26 | Helical | ||||
Sequence: IVWGLAFTASVVALVQAFLFY | ||||||
Transmembrane | 60-79 | Helical | ||||
Sequence: VVGVFFVVIVILLSIAAFVL | ||||||
Transmembrane | 85-105 | Helical | ||||
Sequence: FVPFAFLTGGFFSGLAGWFGM | ||||||
Transmembrane | 135-159 | Helical | ||||
Sequence: AVMGLTVVGLGLIDITVWFGFLYYV | ||||||
Transmembrane | 171-191 | Helical | ||||
Sequence: LIDITVTMLCFGMGASAQALF | ||||||
Transmembrane | 250-270 | Helical | ||||
Sequence: YCGSILATAALGVAAFASGSL | ||||||
Transmembrane | 290-311 | Helical | ||||
Sequence: LLLPMAIAGVGIFLSIIGIYLV | ||||||
Transmembrane | 332-349 | Helical | ||||
Sequence: ASTILVVVAAAGLSWWLM | ||||||
Transmembrane | 355-377 | Helical | ||||
Sequence: TLIFGIPGVAFSIVVGLASGWLI | ||||||
Transmembrane | 418-439 | Helical | ||||
Sequence: VWVPVLVVCAATLLAFGCAAGW | ||||||
Transmembrane | 445-470 | Helical | ||||
Sequence: SYFALGLYGVGIAAVGMLSTLGITLA | ||||||
Transmembrane | 514-532 | Helical | ||||
Sequence: GFAIGSAALTALALLAAYI | ||||||
Transmembrane | 647-666 | Helical | ||||
Sequence: VLVGVFLGAMATFVFCAMTM | ||||||
Transmembrane | 714-732 | Helical | ||||
Sequence: MVVPSLLGLVTPLAVGLLL | ||||||
Transmembrane | 738-758 | Helical | ||||
Sequence: LGLLVGTLTCGFCVAIFMANA | ||||||
Transmembrane | 805-826 | Helical | ||||
Sequence: ILIKLMSMVSVVVAGLVVRYSL |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length832
- Mass (Da)86,946
- Last updated2023-02-22 v1
- ChecksumA18C83D18406EB36