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A0A949V464 · A0A949V464_CHLSQ

  • Protein
    Glucose-6-phosphate 1-dehydrogenase
  • Gene
    zwf
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site48NADP+ (UniProtKB | ChEBI)
Binding site91-92NADP+ (UniProtKB | ChEBI)
Binding site158NADP+ (UniProtKB | ChEBI)
Binding site188substrate
Binding site192substrate
Binding site226substrate
Binding site245substrate
Active site250Proton acceptor
Binding site340substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number
  • Short names
    G6PD

Gene names

    • Name
      zwf
    • ORF names
      JZU70_01620

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • LaCa_MAG_11
  • Taxonomic lineage
    Bacteria > Chlorobiota > Chlorobiia > Chlorobiales > Chlorobiaceae > Chlorobium/Pelodictyon group > Chlorobium

Accessions

  • Primary accession
    A0A949V464

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-197Glucose-6-phosphate dehydrogenase NAD-binding
Domain199-476Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    478
  • Mass (Da)
    53,896
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    554FD6F3E6C03BD4A3A3CAB2DB1B294F
MQVKPDNCTIIIFGASSDLAARKLFPSLYELALWGNLPDDYHIIGVGRASLSHEEFRSFMQTKMAVIFPDSVRDEAAYAAFIARIAYVRLDLEEPDGYHALYHEIMTTAAAVCRCANLLFYLATPPSFAPVIVRNLQRADLGEKDGCMDGWRKIIVEKPYGRDLQTARELNSVIGEVFSENRVFRIDHYLGKETVQNIMVFRFSNGIFEPLWNRHHIANVTITIAEDFGIRDRGAFYEEAGLLRDIMQNHALQLLAAVAMEPPVDLSADAVRDEKAKVLRSIRPFTTESVDHSVVLGQYDGYRSEKNVASDSTVETFAAIKFFIDNWRWKDVPFYVKAGKNLAETVTEIVITFQCPPQNYFGPAESCSYTANQVILRIQPEETIAIKFGAKRPGESVITDPVFMKFDYKTSFTEAGLTPYHRLLLDALAGEQMNFIRQDSVEYSWAIIDSIRQAVGSKLPEGYPAHSHGPESVDKIYG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAFLKS010000024
EMBL· GenBank· DDBJ
MBV5302891.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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