A0A940DLX2 · A0A940DLX2_9BACT

Function

function

Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 2/5.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site45substrate
Binding site66substrate
Binding site147NAD+ (UniProtKB | ChEBI)
Active site205
Binding site227NAD+ (UniProtKB | ChEBI)
Active site232
Active site249Proton donor
Binding site252NAD+ (UniProtKB | ChEBI)
Binding site253substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function4-phosphoerythronate dehydrogenase activity
Molecular FunctionNAD binding
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Erythronate-4-phosphate dehydrogenase
  • EC number

Gene names

    • Name
      pdxB
    • ORF names
      IAC07_02210

Organism names

Accessions

  • Primary accession
    A0A940DLX2

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain19-114D-isomer specific 2-hydroxyacid dehydrogenase catalytic
Domain115-251D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    345
  • Mass (Da)
    38,227
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    11F2A4059534D4BD76F07EE588E68E72
MKIVADRNIPFLEGVFEPYADVVYIDGRAISHDDVKDADALIIRTRTRCNASLLDGTKVSMIATATIGTDHIDFGYCNAHGIEVHNAQGCNAGGVMQYVFSALYGTASRKFIKLSPGDTVGIVGVGNVGKKIEHMARHIGFNVLRCDPPRAREEGEDGFCPLEHLLLNSKVVTLHVPLNDSTRGMADENFFSLMRPGAFFINTSRGEVMSDSALMDAAPKLGPVIIDTWNNEPDINRSLLDITDIATPHIAGYSYQGKQNGTASSVQTVARHFGISPLYDFFPASDEPDSRPVHLDLRGKNQGEITSILQYNYPVFTDDFMLRVDPGSFERLRTEYRYRREIYVD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JADIMJ010000036
EMBL· GenBank· DDBJ
MBO8453522.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help