A0A934WMK1 · A0A934WMK1_9BURK
- ProteinMultifunctional fusion protein
- GenearoA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids685 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
Catalytic activity
- 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphateThis reaction proceeds in the forward direction.
Pathway
Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 25 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 25 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 26 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 30 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 118 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 146 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 194 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 195 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 196 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 196 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 223 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Active site | 343 | Proton acceptor | |||
Binding site | 343 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 370 | 3-phosphoshikimate (UniProtKB | ChEBI) | |||
Binding site | 374 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 416 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 443 | phosphoenolpyruvate (UniProtKB | ChEBI) | |||
Binding site | 470-478 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | (d)CMP kinase activity | |
Molecular Function | 3-phosphoshikimate 1-carboxyvinyltransferase activity | |
Molecular Function | ATP binding | |
Biological Process | amino acid biosynthetic process | |
Biological Process | aromatic amino acid family biosynthetic process | |
Biological Process | chorismate biosynthetic process | |
Biological Process | phosphorylation | |
Biological Process | pyrimidine nucleotide metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameMultifunctional fusion protein
Including 2 domains:
- Recommended name3-phosphoshikimate 1-carboxyvinyltransferase
- EC number
- Alternative names
- Recommended nameCytidylate kinase
- EC number
- Short namesCK
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Ramlibacter
Accessions
- Primary accessionA0A934WMK1
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 16-67 | Enolpyruvate transferase | |||
Region | 74-111 | Disordered | |||
Domain | 110-452 | Enolpyruvate transferase | |||
Domain | 467-674 | Cytidylate kinase | |||
Sequence similarities
Belongs to the EPSP synthase family.
Belongs to the cytidylate kinase family. Type 1 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length685
- Mass (Da)73,089
- Last updated2023-02-22 v1
- MD5 Checksum60873A1FE6B80109DD2EADF9AF72E9E5
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAEPWM010000004 EMBL· GenBank· DDBJ | MBK6006710.1 EMBL· GenBank· DDBJ | Genomic DNA |