A0A934WMK1 · A0A934WMK1_9BURK

Function

function

Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site253-phosphoshikimate (UniProtKB | ChEBI)
Binding site25phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site263-phosphoshikimate (UniProtKB | ChEBI)
Binding site303-phosphoshikimate (UniProtKB | ChEBI)
Binding site118phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site146phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site1943-phosphoshikimate (UniProtKB | ChEBI)
Binding site1953-phosphoshikimate (UniProtKB | ChEBI)
Binding site1963-phosphoshikimate (UniProtKB | ChEBI)
Binding site196phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site2233-phosphoshikimate (UniProtKB | ChEBI)
Active site343Proton acceptor
Binding site3433-phosphoshikimate (UniProtKB | ChEBI)
Binding site3703-phosphoshikimate (UniProtKB | ChEBI)
Binding site374phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site416phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site443phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site470-478ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function(d)CMP kinase activity
Molecular Function3-phosphoshikimate 1-carboxyvinyltransferase activity
Molecular FunctionATP binding
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process
Biological Processphosphorylation
Biological Processpyrimidine nucleotide metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Multifunctional fusion protein

Including 2 domains:

  • Recommended name
    3-phosphoshikimate 1-carboxyvinyltransferase
  • EC number
  • Alternative names
    • 5-enolpyruvylshikimate-3-phosphate synthase
      (EPSP synthase
      ; EPSPS
      )
  • Recommended name
    Cytidylate kinase
  • EC number
  • Short names
    CK
  • Alternative names
    • Cytidine monophosphate kinase
      (CMP kinase
      )

Gene names

    • Name
      aroA
    • Synonyms
      cmk
    • ORF names
      JJB11_11465

Organism names

  • Taxonomic identifier
  • Strain
    • KACC 17527
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Ramlibacter

Accessions

  • Primary accession
    A0A934WMK1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain16-67Enolpyruvate transferase
Region74-111Disordered
Domain110-452Enolpyruvate transferase
Domain467-674Cytidylate kinase

Sequence similarities

Belongs to the EPSP synthase family.
Belongs to the cytidylate kinase family. Type 1 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    685
  • Mass (Da)
    73,089
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    60873A1FE6B80109DD2EADF9AF72E9E5
MFATAFLDLPPLEEAAGKVILPGSKSISNRVLLLAALSEGTTVIHDLLESDDTKVMLDALRALGCSVVHSGPSLEITGFSPPPSGGRSGGGRSAPERPHPNPPPKGEGAKRLFLGNAGTAMRPLTAALALLGGDYEVSGIARMHERPIGDLVDALRQLGCRIDYLGNEGYPPLRIHPADALQLAAPISVRGDVSSQFLTALLMALPLVATQDIVIEVVGDLISKPYIEITLNMLQRFGIAVRRDGWQRFIIPAGSRYQSPGEIHVEADASSASYFVALGALAAVDQPVRIEGVGADSIQGDIRFLDAAQAMGAQVTSGPNWLEVKRGAWPLKAIDLDCNHIPDAAMTLAVMALYADGISTLRNIASWRVKETDRLAAMAAELRKLGATVVEGADFLRVAPPATWTSAAIHTYDDHRMAMCFALAAFNPAGTHVRILDPKCVAKTFPDYFEALFSVTRTDAPHIPVLCVDGPTASGKGTLASQVAHRLGYHYLDSGALYRITGHAAVHAGLSLDVAHEHTIARMAETLPIVFHADRVLLDGVDVTDAIRTEEAGMNASKVSALPAVRTALVALQQSFRKLPGLVADGRDMGTVIFPDAPLKVYLTASAAQRAERRYKQLISKGIPATLPALRADLEARDARDSNRAVAPLKPAEDALLLDNSGQSVEESVAQVLKWWDEKQAFAPR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAEPWM010000004
EMBL· GenBank· DDBJ
MBK6006710.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help