A0A934TNI9 · A0A934TNI9_9BURK

  • Protein
    Phospho-N-acetylmuramoyl-pentapeptide-transferase
  • Gene
    mraY
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site218Mg2+ (UniProtKB | ChEBI)
Binding site293Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionmetal ion binding
Molecular Functionphospho-N-acetylmuramoyl-pentapeptide-transferase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospho-N-acetylmuramoyl-pentapeptide-transferase
  • EC number
  • Alternative names
    • UDP-MurNAc-pentapeptide phosphotransferase

Gene names

    • Name
      mraY
    • ORF names
      JJB11_00055

Organism names

  • Taxonomic identifier
  • Strain
    • KACC 17527
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Ramlibacter

Accessions

  • Primary accession
    A0A934TNI9

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane29-48Helical
Transmembrane69-94Helical
Transmembrane100-117Helical
Transmembrane137-156Helical
Transmembrane195-213Helical
Transmembrane225-245Helical
Transmembrane265-282Helical
Transmembrane289-310Helical
Transmembrane316-339Helical
Transmembrane370-389Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 4 family. MraY subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    392
  • Mass (Da)
    43,119
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    28175D89BB25E053189A4F39AACB4F32
MIVSLAAWMQSHGHEFGFFRVFQYITFRAVMAAMTALLIGIIAGPWVIRRLTALKIGQPVRGYAMDTHLVKSGTPTMGGVLILISIGVSTLLWFDWTNRFVWIVMLVTLGFGAIGWVDDWRKVVNKDPEGMPSREKYFWQSVIGLVAALYLAFSVSESSNTRVIGLFFEWVRSGFDMTLPPKAGLLVPFVKEVNYPLGVFGFMILTYLVIVGSSNAVNLTDGLDGLAIMPVVMVGSALGVFAYVTGSSVFSRYLLLPYIPGSGELLIFCAAVAGAGLAFLWFNAHPAQVFMGDVGALALGGALGTIAVIVRQEIVLAIMGGIFVVEALSVMAQVLYFKYTKRKYGQGRRILLMAPLHHHFEKTGWKETQVVIRFWIITMLLCLVGLSTLKLR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAEPWM010000001
EMBL· GenBank· DDBJ
MBK6004467.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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