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A0A928YFV9 · A0A928YFV9_9BACT

  • Protein
    NADH-quinone oxidoreductase subunit B
  • Gene
    nuoB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site55[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site56[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site121[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site150[4Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functioniron ion binding
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH:ubiquinone reductase (non-electrogenic) activity
Molecular Functionquinone binding
Biological Processaerobic respiration
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-quinone oxidoreductase subunit B
  • EC number
  • Alternative names
    • NADH dehydrogenase I subunit B
    • NDH-1 subunit B

Gene names

    • Name
      nuoB
    • ORF names
      HS127_18420

Organism names

Accessions

  • Primary accession
    A0A928YFV9

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Keywords

Interaction

Subunit

NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain55-164NADH:ubiquinone oxidoreductase-like 20kDa subunit

Sequence similarities

Belongs to the complex I 20 kDa subunit family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    212
  • Mass (Da)
    23,999
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    38E3DEF680BFE15B5A488D0065C83453
MKWWLTKSSDQTKTVSGTSSFEEAVQKTVVLCNLQNLIAWGRKNSLWPFNFGLSCCYVEMATSLTSKYDIARFGAEVIRGTPREADVMITAGTIFIKMAPIIKRLYEQMMEPRWIISMGSCSNSGGMYDIYSVVQGVDKFMPVDVYVPGCPPRPDAFMEGLLMLRDSVGKEKRPLSWFTGPQGITRMDPVSMKELKHENRMKMTKIKPPSEI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABTUX010000005
EMBL· GenBank· DDBJ
MBE7549020.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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