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A0A927SEZ8 · A0A927SEZ8_9FIRM

  • Protein
    ATP-dependent protease subunit HslV
  • Gene
    hslV
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP-dependent cleavage of peptide bonds with broad specificity.
    EC:3.4.25.2 (UniProtKB | ENZYME | Rhea)

Activity regulation

Allosterically activated by HslU binding.

Features

Showing features for active site, binding site.

117920406080100120140160
Type
IDPosition(s)Description
Active site8
Binding site164Na+ (UniProtKB | ChEBI)
Binding site167Na+ (UniProtKB | ChEBI)
Binding site170Na+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentHslUV protease complex
Cellular Componentproteasome core complex
Molecular Functionmetal ion binding
Molecular Functionthreonine-type endopeptidase activity
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent protease subunit HslV
  • EC number

Gene names

    • Name
      hslV
    • ORF names
      E7316_00375

Organism names

Accessions

  • Primary accession
    A0A927SEZ8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.

Family & Domains

Sequence similarities

Belongs to the peptidase T1B family. HslV subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    179
  • Mass (Da)
    18,941
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    032AEEC6998BD8C4BCD750553CE496D3
MSSPFRGTTICGVKRNGSIAIAGDGQVTMGEKTVFKSHAHKVRRIYGGEVLVGFAGSTSDAFTLCEMFEEKLTQCGGNLERAAVAMAQNWRGNQTMRQLESLMIVANKETMLILSGTGDVIEPDDGVAAIGSGGNYALAAARALVENTELSAREIAEKALHIAASICVFTNNNIIVDEA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SVGJ01000001
EMBL· GenBank· DDBJ
MBE5802949.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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