A0A927KEG5 · A0A927KEG5_9XANT
- ProteinRibonuclease PH
- Generph
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids242 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
Catalytic activity
- tRNA(n+1) + phosphate = tRNA(n) + a ribonucleoside 5'-diphosphate
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 89 | phosphate (UniProtKB | ChEBI); substrate | |||
Binding site | 127-129 | phosphate (UniProtKB | ChEBI); substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3'-5'-RNA exonuclease activity | |
Molecular Function | tRNA binding | |
Molecular Function | tRNA nucleotidyltransferase activity | |
Biological Process | rRNA catabolic process | |
Biological Process | rRNA processing | |
Biological Process | tRNA processing |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease PH
- EC number
- Short namesRNase PH
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Xanthomonas
Accessions
- Primary accessionA0A927KEG5
Proteomes
Interaction
Subunit
Homohexameric ring arranged as a trimer of dimers.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length242
- Mass (Da)26,062
- Last updated2023-02-22 v1
- MD5 ChecksumEC924F6662A15FC1AAB0D78C7343DF37
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACVAP010000001 EMBL· GenBank· DDBJ | MBD9367263.1 EMBL· GenBank· DDBJ | Genomic DNA |