A0A927JDI0 · A0A927JDI0_9ACTN

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site109-112substrate
Active site111Proton acceptor
Binding site131K+ (UniProtKB | ChEBI)
Binding site134ATP (UniProtKB | ChEBI)
Binding site186substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      HT102_12455

Organism names

  • Taxonomic identifier
  • Strain
    • G463
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Hoyosellaceae > Lolliginicoccus

Accessions

  • Primary accession
    A0A927JDI0

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region260-284Disordered

Sequence similarities

Belongs to the type III pantothenate kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    284
  • Mass (Da)
    30,066
  • Last updated
    2023-02-22 v1
  • Checksum
    8830986213089E18
MLLAVDVGNTNIVLGLFEGTGEDARLVADWRVRTDPRTTADELALMVRGLLGPLAASVTGVSGLSTVPSLLRQLRIVLDRYWPGVPHVLVEPGVKTGVPLLVDNPKEVGADRVVNALAAYHACHSACIVVDFGTSTSVDVVSASGELLGGAIAPGIEISVDALASQAAALRKVEMVRPRSVIGKNTVECLQAGVVFGFAGQVDGLVRRVQREAGLQEATVIATGGLASLVLEECETVLRHEPELTLTGLRLVFERNMAAQRRPHRPSVAHNPRPSSLHPQRAAR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACYWE010000007
EMBL· GenBank· DDBJ
MBD8507296.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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