A0A927JCB8 · A0A927JCB8_9ACTN

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Probably binds two magnesium or manganese ions per subunit.

Features

Showing features for binding site, active site, site.

127020406080100120140160180200220240260
Type
IDPosition(s)Description
Binding site10Mg2+ 1 (UniProtKB | ChEBI)
Binding site38Mg2+ 1 (UniProtKB | ChEBI)
Active site117
Active site157Proton donor/acceptor
Binding site157Mg2+ 1 (UniProtKB | ChEBI)
Binding site159Mg2+ 1 (UniProtKB | ChEBI)
Site159Transition state stabilizer
Site231Important for catalytic activity
Binding site260Mg2+ 1 (UniProtKB | ChEBI)
Active site261Proton acceptor
Binding site261Mg2+ 1 (UniProtKB | ChEBI)
Site261Interaction with DNA substrate

GO annotations

AspectTerm
Molecular Functiondouble-stranded DNA 3'-5' DNA exonuclease activity
Molecular Functionmetal ion binding
Biological ProcessDNA repair

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Exodeoxyribonuclease III
      (EC:3.1.11.2
      )

Gene names

    • Name
      xth
    • ORF names
      HT102_08400

Organism names

  • Taxonomic identifier
  • Strain
    • G463
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Hoyosellaceae > Lolliginicoccus

Accessions

  • Primary accession
    A0A927JCB8

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-261Endonuclease/exonuclease/phosphatase

Sequence similarities

Belongs to the DNA repair enzymes AP/ExoA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    270
  • Mass (Da)
    29,307
  • Last updated
    2023-02-22 v1
  • Checksum
    E2C1C58A71D0BF0B
MPGIIVSTVNVNGVRAAARKGLLEWLSSTEAGIVCLQETRADDKQLATALAPVLDEGWMLTSAEPAAKGRNGVAVLSRTAPAEVRIGFGSDEFDDAGRYLEADFEHGGQPLTVASLYLPSGEANTPKQDEKDRFLAEFGAFLAVRARSGREMVVCGDWNSAHAEADIKNWKGNLKSSGFLPHEREWLTGIIGDGTPWTDVVRALHPGVEGPYSWWSYRGKAFDNDAGWRIDYQVATGALADRAADARVERAATYDARWSDHAPVTVRYAA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACYWE010000004
EMBL· GenBank· DDBJ
MBD8506503.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp