A0A927JB62 · A0A927JB62_9ACTN
- ProteinDelta-aminolevulinic acid dehydratase
- GenehemB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids326 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- 2 5-aminolevulinate = porphobilinogen + 2 H2O + H+
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 198 | Schiff-base intermediate with substrate | |||
Binding site | 208 | 5-aminolevulinate 1 (UniProtKB | ChEBI) | |||
Binding site | 219 | 5-aminolevulinate 1 (UniProtKB | ChEBI) | |||
Binding site | 235 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 250 | Schiff-base intermediate with substrate | |||
Binding site | 276 | 5-aminolevulinate 2 (UniProtKB | ChEBI) | |||
Binding site | 315 | 5-aminolevulinate 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | porphobilinogen synthase activity | |
Molecular Function | zinc ion binding | |
Biological Process | heme biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDelta-aminolevulinic acid dehydratase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Hoyosellaceae > Lolliginicoccus
Accessions
- Primary accessionA0A927JB62
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homooctamer.
Structure
Sequence
- Sequence statusComplete
- Length326
- Mass (Da)34,727
- Last updated2023-02-22 v1
- ChecksumD26883902BA877D9
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACYWE010000002 EMBL· GenBank· DDBJ | MBD8505930.1 EMBL· GenBank· DDBJ | Genomic DNA |