A0A927JB62 · A0A927JB62_9ACTN

  • Protein
    Delta-aminolevulinic acid dehydratase
  • Gene
    hemB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.

Features

Showing features for active site, binding site.

132650100150200250300
Type
IDPosition(s)Description
Active site198Schiff-base intermediate with substrate
Binding site2085-aminolevulinate 1 (UniProtKB | ChEBI)
Binding site2195-aminolevulinate 1 (UniProtKB | ChEBI)
Binding site235Mg2+ (UniProtKB | ChEBI)
Active site250Schiff-base intermediate with substrate
Binding site2765-aminolevulinate 2 (UniProtKB | ChEBI)
Binding site3155-aminolevulinate 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionporphobilinogen synthase activity
Molecular Functionzinc ion binding
Biological Processheme biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Delta-aminolevulinic acid dehydratase
  • EC number

Gene names

    • Name
      hemB
    • ORF names
      HT102_05470

Organism names

  • Taxonomic identifier
  • Strain
    • G463
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Hoyosellaceae > Lolliginicoccus

Accessions

  • Primary accession
    A0A927JB62

Proteomes

Subcellular Location

Interaction

Subunit

Homooctamer.

Family & Domains

Sequence similarities

Belongs to the ALAD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    326
  • Mass (Da)
    34,727
  • Last updated
    2023-02-22 v1
  • Checksum
    D26883902BA877D9
MYPTDRPRRLRTTPALRRLVAEHDVAPRQLVLPMFVADGLAEPRPIASMPGVVQHTLETARRAAEDATEAGVGGIMLFGVPEPAAKDADGSAGCDPSGILNRSLRQLRADLGDSTVLMADTCLDEFTDHGHCGVLDEQGRVDNDATLEHYARLAVAQASAGAHVVSPSGMMDGQVGRIRGALDDAGHADVAILAYSAKYASALYGPFREAVGSSLKGTRASYQQDPANARESLREVTLDLAEGADMVMVKPAMMYLDIIRDVAAASTVPVAAYQVSGEYSMISAAAERGWIDLDRAILESLLSIHRAGAGIILTYWAADAARMLWQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACYWE010000002
EMBL· GenBank· DDBJ
MBD8505930.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp