A0A927GNY7 · A0A927GNY7_STRGL

  • Protein
    Glucosamine-6-phosphate deaminase
  • Gene
    nagB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).

Pathway

Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 5/5.

Features

Showing features for active site, site.

TypeIDPosition(s)Description
Active site67Proton acceptor; for enolization step
Active site136For ring-opening step
Active site138Proton acceptor; for ring-opening step
Active site143For ring-opening step
Site146Part of the allosteric site
Site153Part of the allosteric site
Site155Part of the allosteric site
Site156Part of the allosteric site

GO annotations

AspectTerm
Molecular Functionglucosamine-6-phosphate deaminase activity
Biological Processcarbohydrate metabolic process
Biological ProcessN-acetylglucosamine metabolic process
Biological ProcessN-acetylneuraminate catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucosamine-6-phosphate deaminase
  • EC number
  • Alternative names
    • GlcN6P deaminase
      (GNPDA
      )
    • Glucosamine-6-phosphate isomerase

Gene names

    • Name
      nagB
    • ORF names
      ID875_15955

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • QF2
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A927GNY7

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-226Glucosamine/galactosamine-6-phosphate isomerase

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    261
  • Mass (Da)
    27,222
  • Last updated
    2023-02-22 v1
  • Checksum
    82ED5357A2D64131
MEVVIVPDATAGGELIAEAIAALLDRKPDALLGVATGSTPLPIYRALAAKVASGAVDASRARICQLDEYVGLPAGHPESYRSVVLREVVEPLGLSEASFMGPDGSAEDVQAACEAYDKALAEAGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRVDNARFFDDDIEQVPHHVITQGIGTILDARHPILLATGEGKAEAVAQTVEGPVASIVPASALQLHPHATVVVDEAAASKLKLADYFRATYAAKPAWQGL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACWUS010000001
EMBL· GenBank· DDBJ
MBD2829384.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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