A0A927BM48 · A0A927BM48_STRGL

Function

function

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site23Zn2+ (UniProtKB | ChEBI); catalytic
Binding site25Zn2+ (UniProtKB | ChEBI); catalytic
Binding site25substrate
Binding site27substrate
Binding site185substrate
Binding site212Zn2+ (UniProtKB | ChEBI); catalytic
Active site215Proton donor
Site236Important for catalytic activity
Binding site304Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenosine deaminase activity
Molecular Functionzinc ion binding
Biological Processadenosine catabolic process
Biological Processhypoxanthine salvage
Biological Processinosine biosynthetic process
Biological Processnucleotide metabolic process
Biological Processpurine ribonucleoside monophosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosine deaminase
  • EC number
  • Alternative names
    • Adenosine aminohydrolase

Gene names

    • Name
      add
    • ORF names
      ID875_14240

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • QF2
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces

Accessions

  • Primary accession
    A0A927BM48

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain18-358Adenosine deaminase

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    384
  • Mass (Da)
    42,482
  • Last updated
    2023-02-22 v1
  • Checksum
    DDCF52DDC4388ECA
MTSQTPNVPDSDQIRRAPKVLLHDHLDGGLRPGTVVELARAQGYDSLPETEPDKLGVWFREAADSGSLPRYLETFAHTCAVMQTREALFRVAAECAEDLAEDGVVYAEIRYAPEQHLEGGLTLEEVVEAVNEGFREGERVARANGHRIRVGALLTAMRHAARALEIAELANSYRDQGVVGFDIAGAEAGFPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSIWQALQWCGADRLGHGVRIIDDIEVADDGSVTLGRLASYVRDKRIPLEMCPTSNLQTGAATSYAEHPIGLLRKLHFRITVNTDNRLMSGTSMSQEFERLTETFGYTLDDMQWFTVNAMKSAFIPFDERLAMINDVVKPGYAELKSEWLFRQTAVTSASAASAS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACWUS010000001
EMBL· GenBank· DDBJ
MBD2829180.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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