A0A926M1U7 · A0A926M1U7_9PROT

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site103-106substrate
Active site105Proton acceptor
Binding site124K+ (UniProtKB | ChEBI)
Binding site127ATP (UniProtKB | ChEBI)
Binding site178substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      IDH20_01805

Organism names

Accessions

  • Primary accession
    A0A926M1U7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    248
  • Mass (Da)
    27,933
  • Last updated
    2023-02-22 v1
  • Checksum
    69641D25330DAB2C
MYILGDIGNSETKIFLVNSNYKILRNINFSSKGINNKILNIKFNSLIKDFKIIKKILFCSVVPKNFYLIKNFLLNKTKNKCYEIKNLNLRSLININVNYKQVGSDRLTNAISLLNRKDNFIILDFGTATTFDVVIKKTYKGGIIAPGIKISLNTLSDKAALIPKIDLKKIKKIIGNDTISAVRSGFFWGYSGLIDNIINLIKKETGKSFKLIITGGFSGLFKDSIKTKVIQDKDITIKGLIKISKLIK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACWEI010000004
EMBL· GenBank· DDBJ
MBD1140887.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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