A0A926M1L3 · A0A926M1L3_9PROT

Function

function

Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site73-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site9-101-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site183-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Active site43Proton acceptor
Binding site451-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Binding site501-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Active site70Proton acceptor
Binding site1001-deoxy-D-xylulose 5-phosphate (UniProtKB | ChEBI)
Site151Transition state stabilizer
Active site192Proton donor
Binding site1933-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)
Binding site214-2153-amino-2-oxopropyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionpyridoxine 5'-phosphate synthase activity
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyridoxine 5'-phosphate synthase
  • EC number
  • Short names
    PNP synthase

Gene names

    • Name
      pdxJ
    • ORF names
      IDH20_01095

Organism names

Accessions

  • Primary accession
    A0A926M1L3

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homooctamer; tetramer of dimers.

Family & Domains

Sequence similarities

Belongs to the PNP synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    241
  • Mass (Da)
    27,590
  • Last updated
    2023-02-22 v1
  • Checksum
    EF93B6F03B2C592A
MKRLGVNIDHVATIRNARGEKHPSPFLAAKFAKKAGADSITIHLREDRRHIKDLDAKKICSIKGLLVNLEISTNLNMIKSAIKLRPDFVCIVPENRKEITTEGGLNLRKNKRRLKQILSRFKKEKIRTSLFINPIIDDIRISKELETNCIEIHTGHLANLIKSKKNYTKELKKITKCSILAKNLGIEVHAGHGLDYKTTRILRNIKEIEEYNIGHYIIGESIFSGLSKVIKNFNKIIKNRK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JACWEI010000002
EMBL· GenBank· DDBJ
MBD1140752.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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