A0A926M1D9 · A0A926M1D9_9PROT
- ProteinSuccinate dehydrogenase flavoprotein subunit
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids591 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- a quinone + succinate = fumarate + a quinol
Cofactor
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (bacterial route): step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 17-22 | FAD (UniProtKB | ChEBI) | ||||
Sequence: GAGGSG | ||||||
Binding site | 40-55 | FAD (UniProtKB | ChEBI) | ||||
Sequence: SKVFPTRSHTSAAQGG | ||||||
Binding site | 223 | FAD (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 244 | substrate | ||||
Sequence: H | ||||||
Binding site | 256 | substrate | ||||
Sequence: T | ||||||
Active site | 288 | Proton acceptor | ||||
Sequence: R | ||||||
Binding site | 355 | substrate | ||||
Sequence: H | ||||||
Binding site | 387 | FAD (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 398 | substrate | ||||
Sequence: R | ||||||
Binding site | 403-404 | FAD (UniProtKB | ChEBI) | ||||
Sequence: SL |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | electron transfer activity | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | succinate dehydrogenase activity | |
Biological Process | anaerobic respiration | |
Biological Process | electron transport chain | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSuccinate dehydrogenase flavoprotein subunit
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Candidatus Pelagibacterales
Accessions
- Primary accessionA0A926M1D9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 48 | Tele-8alpha-FAD histidine | ||||
Sequence: H |
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 12-404 | FAD-dependent oxidoreductase 2 FAD binding | ||||
Sequence: DVVVLGAGGSGLRAAVGLSEAGLKTACISKVFPTRSHTSAAQGGISASLGNMGEDDWRWHMYDTVKGADWLGDQDSIEYLCKEAPKAVIELEKYGVPFSRTEDGKIYQRPFGGMTKNYGNGIVQRTCAAADRTGHAILHTLYGQALKHKTEFFIEYFALDLLMKDGECKGLIAWNLNDGTIHRFRAHSVIIATGGYGKVYYSATSAHTCTGDGNAMVLRAGLPLQDMEFVQFHPTGIYGHGTLITEGARGEGGYLTNSKGERFMERYAPKTKDLASRDVVSRSMSIEINEGRGVGKDQDHVHLNLSHLDKEIIESRLPGITDAARLFANVDITKEPIPVVPTVHYNMGGIPTNYKGEVLTVNGSEKTVPGLMAIGEAACVSVHGANRLGSNSL | ||||||
Domain | 460-591 | Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal | ||||
Sequence: LSMQKTMQSKCAVFRTEKTLKEGVEDIRKTYDGLNSMSVKDKSLIFNTDLVESLEFDNLIRQAVVTVDSAYHRKESRGAHAREDFPKRDDEKFMQHTLAWCNGKETKISYREVHKSTLTNEVQYFPPQERVY |
Sequence similarities
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length591
- Mass (Da)65,193
- Last updated2023-02-22 v1
- Checksum5D6FE3DDCDA3F1A9
Keywords
- Technical term