A0A922I6R7 · A0A922I6R7_DERFA

Function

function

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site.

122120406080100120140160180200220
TypeIDPosition(s)Description
Active site76Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentmitochondrion
Molecular Functionthioredoxin peroxidase activity
Biological Processcell redox homeostasis
Biological Processcellular response to stress
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    thioredoxin-dependent peroxiredoxin
  • EC number

Gene names

    • Name
      TPX1
    • ORF names
      DERF_006078

Organism names

  • Taxonomic identifier
  • Strain
    • Derf
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides

Accessions

  • Primary accession
    A0A922I6R7

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain31-189Thioredoxin

Sequence similarities

Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    221
  • Mass (Da)
    25,097
  • Last updated
    2023-02-22 v1
  • Checksum
    B66B8E79A802C02A
MASLLRQFIRPASISLAKRNVNLLNTRFMSAFVQQPAPDFKATAVVDKQFKDIKLADFQGKYLVLFFYPLDFTFVCPTEIIAFNDRLQEFRDLQTEVVAVSVDSHFSHLAWCNTPRKQGGLGDMKMPIIADLTKKISGDYGVLLPEAGVALRGLFIIDTKGIVRQITINDLPVGRSVDETLRLIKAFQYTDKHGEVCPANWQPDRPTIDPRNAREYFEKQN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ASGP02000002
EMBL· GenBank· DDBJ
KAH9522512.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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