A0A922I6M3 · A0A922I6M3_DERFA
- ProteinUncharacterized protein
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1061 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Cellular Component | host cell presynaptic membrane | |
Cellular Component | neuron projection | |
Cellular Component | other organism cell membrane | |
Cellular Component | plasma membrane | |
Cellular Component | postsynapse | |
Molecular Function | chloride channel activity | |
Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | |
Molecular Function | ligand-gated monoatomic anion channel activity | |
Molecular Function | toxin activity | |
Molecular Function | transmembrane signaling receptor activity | |
Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | |
Biological Process | exocytosis |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides
Accessions
- Primary accessionA0A922I6M3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 258-280 | Helical | ||||
Sequence: FYFTTVFVPGMVLVTSSFISFWL | ||||||
Transmembrane | 321-344 | Helical | ||||
Sequence: LWDFVCMFFIYASMIEFIIVNYIY | ||||||
Transmembrane | 558-577 | Helical | ||||
Sequence: VFTLTFGLFSFFYFLTYAFI |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-24 | |||||
Sequence: MIGTWKLISHILTLLISIPNIIES | ||||||
Chain | PRO_5037021824 | 25-1061 | ||||
Sequence: KLNNYDKIGQHFNLTDKQILDQIIIPDKYDYRMRPEEKTIVNLSILILTLSSPDESSVTYEIGFVLMQRWYDPRLRFELPDALLDTKNSNSIYLNGLKHTDRIWIPDTYFIKHGEFRHTTDQFDPLHITLKIFPNGTVLYTTRRNMILTCEGNLRIFPFDSPKCFFGIESLSHEKDQIRFQWDEQVSIKTSDSLKTINAYMTRNETNRCNKRHSWRREFSCLSVLLIFSRDQSFYFTTVFVPGMVLVTSSFISFWLDVNAVPARVMIGVTTMLNFCTTTNSFRSKLPVVSNLYAMNLWDFVCMFFIYASMIEFIIVNYIYRKGNQQQQQQQQRTSTRSKQDSFTRQDFSFRNKSLRNIYNRDEPTPLPTSSITREHMDNLPKKKFRRQQTTELDIRIAKSNYARAATTNIPTAATATTTATSSALAMTTGTDTGSESENIDPLSGDYYRPNYQRRSAIGSTTTALNQSFRVRVNNNNNMQPTLSEEQETEKLNVQQMKNIVMEWIKRPYLFTASEQYSSNEQLARSIDHISKTVFTLTFGLFSFFYFLTYAFIKPAQLDDWIEKEFEASDWYHRVTMMTMDHHHHNNHHSMSHIQMNAMDISETYQATNSIQLRTHPTHATINFSELGKKLLESARNGDSEEVIELINSGAPFTTDWLGASPLHYAAQYGHVETVETLLRSGIAKDARTKIDRTALHVASQEGFLETVNVLINFGCDVDSKDMLKMTPLHWAVQRGHRQIVELLLNSGADVKIINKFDKTPIDVAYSCGHDDYVPLLKSYLGKAKPKINPIDNTMQVKMMKNQAKSRSKSNNTVRNINKPMPHQLVKQEFDEDIVGEIRHVSTSDGFITNSTTSSNVANKNQIIIKRTSLDSSQLQNGSQTLQTTASGKLVLNNTSITSLGNNSNAKKLFAINSPNSNIVLLSSPSSGSSNKLNDSGSQPQVIKRYVINPNQTNSSTIQEKDAEIAKLKEENGKLKKELEEIRSLIISKDLEIERLKKSKTTTNQSTADKQEISSNQPTPSSNSPPTLELEDDEQLD |
Structure
Family & Domains
Features
Showing features for domain, repeat, coiled coil, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 42-234 | Neurotransmitter-gated ion-channel ligand-binding | ||||
Sequence: QILDQIIIPDKYDYRMRPEEKTIVNLSILILTLSSPDESSVTYEIGFVLMQRWYDPRLRFELPDALLDTKNSNSIYLNGLKHTDRIWIPDTYFIKHGEFRHTTDQFDPLHITLKIFPNGTVLYTTRRNMILTCEGNLRIFPFDSPKCFFGIESLSHEKDQIRFQWDEQVSIKTSDSLKTINAYMTRNETNRCN | ||||||
Domain | 265-571 | Neurotransmitter-gated ion-channel transmembrane | ||||
Sequence: VPGMVLVTSSFISFWLDVNAVPARVMIGVTTMLNFCTTTNSFRSKLPVVSNLYAMNLWDFVCMFFIYASMIEFIIVNYIYRKGNQQQQQQQQRTSTRSKQDSFTRQDFSFRNKSLRNIYNRDEPTPLPTSSITREHMDNLPKKKFRRQQTTELDIRIAKSNYARAATTNIPTAATATTTATSSALAMTTGTDTGSESENIDPLSGDYYRPNYQRRSAIGSTTTALNQSFRVRVNNNNNMQPTLSEEQETEKLNVQQMKNIVMEWIKRPYLFTASEQYSSNEQLARSIDHISKTVFTLTFGLFSFFYF | ||||||
Repeat | 682-714 | ANK | ||||
Sequence: LGASPLHYAAQYGHVETVETLLRSGIAKDARTK | ||||||
Repeat | 715-747 | ANK | ||||
Sequence: IDRTALHVASQEGFLETVNVLINFGCDVDSKDM | ||||||
Repeat | 748-780 | ANK | ||||
Sequence: LKMTPLHWAVQRGHRQIVELLLNSGADVKIINK | ||||||
Coiled coil | 975-1009 | |||||
Sequence: NQTNSSTIQEKDAEIAKLKEENGKLKKELEEIRSL | ||||||
Region | 1018-1061 | Disordered | ||||
Sequence: ERLKKSKTTTNQSTADKQEISSNQPTPSSNSPPTLELEDDEQLD | ||||||
Compositional bias | 1024-1053 | Polar residues | ||||
Sequence: KTTTNQSTADKQEISSNQPTPSSNSPPTLE |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,061
- Mass (Da)121,200
- Last updated2023-02-22 v1
- Checksum23EF090D0FE98A01
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1024-1053 | Polar residues | ||||
Sequence: KTTTNQSTADKQEISSNQPTPSSNSPPTLE |
Keywords
- Technical term