A0A922I4A3 · A0A922I4A3_DERFA
- ProteinCalcium ion binding
- Geneclec-78_1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids3518 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | calcium ion binding | |
Molecular Function | Notch binding | |
Molecular Function | serine-type peptidase activity | |
Biological Process | Notch signaling pathway |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides
Accessions
- Primary accessionA0A922I4A3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 3365-3391 | Helical | ||||
Sequence: LIYIASGIGAAVFFIIFMVLLIWMICV |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 118↔130 | |||||
Sequence: CPTGSYHCSNGKC | ||||||
Disulfide bond | 125↔143 | |||||
Sequence: CSNGKCINNAWKCDGDDDC | ||||||
Disulfide bond | 137↔152 | |||||
Sequence: CDGDDDCEDRSDEMDC | ||||||
Disulfide bond | 391↔418 | |||||
Sequence: CEINLLSDKGVVTSPAFGVTNYPTNQNC | ||||||
Disulfide bond | 508↔551 | |||||
Sequence: CSPLTIGKNAIASERGSMFGSKVVFTCPVGQEFSTGVLKLETEC | ||||||
Disulfide bond | 661↔688 | |||||
Sequence: CENGYHRRGVPVVVCTSIGQWSGLPPVC | ||||||
Disulfide bond | 1049↔1076 | |||||
Sequence: CDFGYVLQGQRSLACGSNGLWNGTTPQC | ||||||
Disulfide bond | 1960↔1969 | |||||
Sequence: CPAGFSGQSC | ||||||
Disulfide bond | 1998↔2007 | |||||
Sequence: CPAGFSGLQC | ||||||
Disulfide bond | 2019↔2036 | |||||
Sequence: CPEKAMCQNLPGINNINC | ||||||
Disulfide bond | 2038↔2047 | |||||
Sequence: CRTGYEGHNC | ||||||
Disulfide bond | 2079↔2088 | |||||
Sequence: CPAGWTGTHC | ||||||
Disulfide bond | 2117↔2126 | |||||
Sequence: CPPGFTGKRC | ||||||
Disulfide bond | 2133↔2143 | |||||
Sequence: CATNPCIHGLC | ||||||
Disulfide bond | 2154↔2163 | |||||
Sequence: CEPGWNGTRC | ||||||
Disulfide bond | 2231↔2240 | |||||
Sequence: CKPGFVGLQC | ||||||
Disulfide bond | 2252↔2269 | |||||
Sequence: CSPLGTERCIDMDNAYKC | ||||||
Disulfide bond | 2271↔2280 | |||||
Sequence: CHEGFGGELC | ||||||
Disulfide bond | 2309↔2318 | |||||
Sequence: CPLGWNGPRC | ||||||
Disulfide bond | 2347↔2356 | |||||
Sequence: CPSGTDGKRC | ||||||
Disulfide bond | 2385↔2394 | |||||
Sequence: CPAKYTGIGC | ||||||
Disulfide bond | 2424↔2433 | |||||
Sequence: CAPGFTGQNC | ||||||
Disulfide bond | 2462↔2471 | |||||
Sequence: CPFNMTGEDC | ||||||
Disulfide bond | 3327↔3337 | |||||
Sequence: CDDYCINGGKC | ||||||
Disulfide bond | 3331↔3348 | |||||
Sequence: CINGGKCDWKMGMKKPRC | ||||||
Disulfide bond | 3350↔3359 | |||||
Sequence: CLINFYGDRC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-114 | C-type lectin | ||||
Sequence: MCIYGSELVLISDFTQNNFTAALAEASLREAGDDGRSFWIGFESIDQLSTNTIESASGRFVSKYVGFWAYDQPNVDDGQCVRATVIGEHTSNGDAPQSVWSLAECEDLLPFVCQ | ||||||
Domain | 156-268 | CUB | ||||
Sequence: CNYYLQSSGDKVISPNYPNKYDPNSDCKWTLEGPIGSGMILQFSEFDTENNFDQVQILVGGRTEETSTTLATLSGIQNISARAFTTGSNLMIIKFRSDASVEKRGFRASWKTE | ||||||
Domain | 272-390 | CUB | ||||
Sequence: CGGEFTAQTFAQFINSPQYPNYYPGGLECVYVITASQGKTITLEVTELDLEPDTDFLLIRDGLTSKSSPLSRFSGNMTIELSKSHDRYIVSTGNSVYIYFHSNFGVHSRKGFSIRYKAG | ||||||
Domain | 391-507 | CUB | ||||
Sequence: CEINLLSDKGVVTSPAFGVTNYPTNQNCIYHISREKPAEGSVSIVFNEFGVTNEDILQIYDGLDSSTAVPLHPSRGFGTKTKPTGLTLTASSGRMLLLFKTNAMKAARGWSANFSAD | ||||||
Domain | 506-567 | Sushi | ||||
Sequence: ADCSPLTIGKNAIASERGSMFGSKVVFTCPVGQEFSTGVLKLETECLMGGKWSLDTIPNCQE | ||||||
Domain | 568-628 | Sushi | ||||
Sequence: RYCGPVPQIDNGFAVDATNVTYRGIATYQCYAGFAFPSNQRTESIRCGEDGKWGKLPICLA | ||||||
Domain | 629-690 | Sushi | ||||
Sequence: SSCPPISETPRAIQTIMAGSVNRSYGTIIRFECENGYHRRGVPVVVCTSIGQWSGLPPVCER | ||||||
Domain | 691-751 | Sushi | ||||
Sequence: AKCPILPEIKNGYLATNDADRDFYFEDESRVFCNRGYRLEGSSIIKCSSNQSFTGIPICVD | ||||||
Domain | 751-791 | EGF-like | ||||
Sequence: DIDECSPGNSACDISSTICTNTDGGFFCKCKQGFEPNLNCR | ||||||
Domain | 790-947 | F5/8 type C | ||||
Sequence: CRPVSDLGLTTGAIPDSSIRVSSTEPGYKKSDIRLDTIPRSTHFGWCGASPRIGENWVQVDLKAPIVIRGLRIQSVQRLDGSQAYPLTIRLQYADDLTDLFRDYSDISGRPLQFRLAPNGGSGLSIVNLPIPLEVRYIRVMIIEFAVAPCMRFELMGC | ||||||
Domain | 1019-1078 | Sushi | ||||
Sequence: KQCPNLQAPENGKILTLRENYHYNDIITFNCDFGYVLQGQRSLACGSNGLWNGTTPQCVY | ||||||
Domain | 1225-1379 | F5/8 type C | ||||
Sequence: CDRPGYVPYTNDPITCVKSADCRIIKPIGLSTGLIPDSAINATTQPTGWCGQHEPFTYVTVDLKKVYRIKALLVKGVVTNDVVGRPTELRFFYKVREAENFVVYFPNFNLTLSELGNYGELSVINLPATVVARYIILGIVAYHKNPCLKFELLGC | ||||||
Domain | 1398-1483 | HYR | ||||
Sequence: VDKEPPRFQNCPTAPIVVNRGPTGIMPVNYTIPTAIDNSGFIARVEVLPIGFKPPMIVLEDLRVEYRAYDTDGNVAICQVNITLPE | ||||||
Domain | 1484-1567 | HYR | ||||
Sequence: TTPPMLHCPQSYVIELVEEQESYEINFNQTRRLINATDESGEVQITLIPEMDFIPVKGYRNITVLATDRFGNEAVCHFQVSVQP | ||||||
Domain | 1934-1970 | EGF-like | ||||
Sequence: VQGQCSSIQCQNGGLCIVNKHEPYCYCPAGFSGQSCE | ||||||
Domain | 1972-2008 | EGF-like | ||||
Sequence: DIDECQSEPCFNGGTCIDHPQGYSCRCPAGFSGLQCQ | ||||||
Domain | 2010-2048 | EGF-like | ||||
Sequence: EQEECLQDSCPEKAMCQNLPGINNINCLCRTGYEGHNCN | ||||||
Domain | 2050-2089 | EGF-like | ||||
Sequence: TVNPCSNNPSPCENDAICIPLLQGRYHCRCPAGWTGTHCQ | ||||||
Domain | 2091-2127 | EGF-like | ||||
Sequence: NIDDCADDPCLLGAQCTDLVNDFKCDCPPGFTGKRCE | ||||||
Domain | 2129-2164 | EGF-like | ||||
Sequence: KIDLCATNPCIHGLCVDRLFYHECVCEPGWNGTRCE | ||||||
Domain | 2166-2203 | EGF-like | ||||
Sequence: NTNECASSPCENDAECVDLIDGYRCVCDPNSFTGSRCQ | ||||||
Domain | 2205-2241 | EGF-like | ||||
Sequence: EIDACESSPCQNGGTCLDQSIGFRCQCKPGFVGLQCE | ||||||
Domain | 2243-2281 | EGF-like | ||||
Sequence: EVDECVSNPCSPLGTERCIDMDNAYKCQCHEGFGGELCE | ||||||
Domain | 2283-2319 | EGF-like | ||||
Sequence: NIDECSSSPCFNGGTCVDQINSYRCNCPLGWNGPRCE | ||||||
Domain | 2321-2357 | EGF-like | ||||
Sequence: DVGMCDSSPCHNNARCVDLFQDYFCVCPSGTDGKRCQ | ||||||
Domain | 2359-2395 | EGF-like | ||||
Sequence: APQRCIGNPCQNHGMCQDYGSGLNCSCPAKYTGIGCQ | ||||||
Domain | 2397-2434 | EGF-like | ||||
Sequence: EYHVCDEKRCQNGATCQDNYDGTYDCICAPGFTGQNCE | ||||||
Domain | 2436-2472 | EGF-like | ||||
Sequence: DIIDCLPTSCPPSATCIDLTNGFYCKCPFNMTGEDCR | ||||||
Domain | 2718-2800 | HYR | ||||
Sequence: QDKIPPQVLHCPPDMWVISANTSTIVHWDEPQFIDDLRNTQVMEVQKIKPGESLKKGIYDLSYVALDEVGNTARCDFQIHVLR | ||||||
Domain | 3324-3360 | EGF-like | ||||
Sequence: IDVCDDYCINGGKCDWKMGMKKPRCECLINFYGDRCE | ||||||
Compositional bias | 3496-3512 | Basic and acidic residues | ||||
Sequence: RLRKHQYMGKKGDSNSE | ||||||
Region | 3496-3518 | Disordered | ||||
Sequence: RLRKHQYMGKKGDSNSESEDPVN |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length3,518
- Mass (Da)388,721
- Last updated2023-02-22 v1
- Checksum0F360A2C325CC65F
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 3496-3512 | Basic and acidic residues | ||||
Sequence: RLRKHQYMGKKGDSNSE |
Keywords
- Technical term