A0A922I3Q8 · A0A922I3Q8_DERFA

Function

function

Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.

Features

Showing features for site, active site.

TypeIDPosition(s)Description
Site171Transition state stabilizer
Active site251Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionS-methyl-5-thioribose-1-phosphate isomerase activity
Biological ProcessL-methionine salvage from S-adenosylmethionine
Biological ProcessmRNA splicing, via spliceosome

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylthioribose-1-phosphate isomerase
  • EC number
  • Short names
    M1Pi
    ; MTR-1-P isomerase
  • Alternative names
    • S-methyl-5-thioribose-1-phosphate isomerase
    • Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein

Gene names

    • Name
      MRI1
    • ORF names
      DERF_008117

Organism names

  • Taxonomic identifier
  • Strain
    • Derf
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides

Accessions

  • Primary accession
    A0A922I3Q8

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, compositional bias, repeat.

TypeIDPosition(s)Description
Region346-414Disordered
Compositional bias377-410Polar residues
Repeat578-619WD
Repeat620-661WD
Repeat662-703WD
Repeat704-745WD
Repeat787-827WD

Sequence similarities

Belongs to the WD repeat PRL1/PRL2 family.
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    892
  • Mass (Da)
    100,186
  • Last updated
    2023-02-22 v1
  • Checksum
    B815E059D0700989
MATESIIVKDDQIFILNQLLLPTKVSYDRINGVNDAWNAIHQMKIRGAPAIAIIGLLGVSTELSKPDIEAQFDQQSDRLYEFIKQKAEYLCTSRTTAVNIRKEFNELLNFIQQQRQNNVSFALLIDSIRKYCHGIMEKDRMVNKKMAEYGCEHIRKNCHESKCRFNILTHCNTGSLATAGYGTALGVIRELHSNGLLEQAYCTETRPYNQGSRLTAWELLTDNIPSTLICDNMVAWLMASKTIDAIVVGADRVVANGDTANKIGTYQMAILAKHFSIPFYVASPLSTIDPTIDDGTKIPIEERSDLEMKSIGSIQIAPADMKCWNPAFDITPAKLITGGIITERDRDMDSIQTTPVRSRHQHIATPHRPAIRGPPTIKSSTPIQQHQKQSSSSSSQEQQQQQTNDNDGETMVWDESIPKHTRHTLVFRMLKRTHEMFISDMNLLPPFDPEMLNFRHNIKARDQYGPLLLNTNSTGKDDKKMNDKHSQSKALVLKNGNENRISNHGNSPIEELKSKLPAPINRQSQVAVVTTNDNNDSNDKHTKSGQVVLASGLTIAPRKPVQMPKPEWHAPWKLYRVISGHTGWIRCIAVEPGNEWFATGSNDRIIKIWDLASGTLKLSLTGHISPVRGLEVSPRQPYLFSCGEDKMVKCWDLEYNKVVRHYHGHLSGVYCLSLHPTLDILVTGGRDSVARVWDMRTKAQIHSLGGHSNTVASVFCQATDPQVVTGSHDSTIRLWDIVAGKTMATLTNHKKSVRALVAHPRLNTFCSGSINSLKQWTLPEGRFIQNLNGHDSMINALAVNDDNVLVSGGDNGSMFFWDWRTGYNFQRLQSKAQPGSIDSECGIFALHFDQSSSRLITGEADKTIKIYKEDEMANEQTHPIKWEPELLKRKRF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias377-410Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ASGP02000003
EMBL· GenBank· DDBJ
KAH9517441.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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