A0A922I0N0 · A0A922I0N0_DERFA
- Proteinglutamate synthase (NADH)
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2107 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 2 L-glutamate + NAD+ = L-glutamine + 2-oxoglutarate + NADH + H+
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 [3Fe-4S] cluster.
Pathway
Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD+ route): step 1/1.
Energy metabolism; nitrogen metabolism.
Nitrogen metabolism.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 67 | For GATase activity | |||
Binding site | 1194 | [3Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 1200 | [3Fe-4S] cluster (UniProtKB | ChEBI) | |||
Binding site | 1205 | [3Fe-4S] cluster (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3 iron, 4 sulfur cluster binding | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | FMN binding | |
Molecular Function | glutamate synthase (NADH) activity | |
Molecular Function | iron ion binding | |
Biological Process | glutamate biosynthetic process | |
Biological Process | glutamine metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameglutamate synthase (NADH)
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides
Accessions
- Primary accessionA0A922I0N0
Proteomes
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 33-57 | Disordered | |||
Domain | 67-462 | Glutamine amidotransferase type-2 | |||
Sequence similarities
Belongs to the glutamate synthase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,107
- Mass (Da)236,103
- Last updated2023-02-22 v1
- Checksum164BFD136C10A070
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
ASGP02000004 EMBL· GenBank· DDBJ | KAH9511696.1 EMBL· GenBank· DDBJ | Genomic DNA |