A0A922I0N0 · A0A922I0N0_DERFA

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FAD (UniProtKB | Rhea| CHEBI:57692 )

FMN (UniProtKB | Rhea| CHEBI:58210 )

[3Fe-4S] cluster (UniProtKB | Rhea| CHEBI:21137 )

Note: Binds 1 [3Fe-4S] cluster.

Pathway

Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD+ route): step 1/1.
Energy metabolism; nitrogen metabolism.
Nitrogen metabolism.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site67For GATase activity
Binding site1194[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1200[3Fe-4S] cluster (UniProtKB | ChEBI)
Binding site1205[3Fe-4S] cluster (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function3 iron, 4 sulfur cluster binding
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctionFMN binding
Molecular Functionglutamate synthase (NADH) activity
Molecular Functioniron ion binding
Biological Processglutamate biosynthetic process
Biological Processglutamine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    glutamate synthase (NADH)
  • EC number

Gene names

    • ORF names
      DERF_010135

Organism names

  • Taxonomic identifier
  • Strain
    • Derf
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides

Accessions

  • Primary accession
    A0A922I0N0

Proteomes

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region33-57Disordered
Domain67-462Glutamine amidotransferase type-2

Sequence similarities

Belongs to the glutamate synthase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,107
  • Mass (Da)
    236,103
  • Last updated
    2023-02-22 v1
  • Checksum
    164BFD136C10A070
MASTERFNNNNNDNDDDGSTTILDHLNNENITINNNNNNNDDDTKRVHQSSLSTRSLWNPNEEKAACGVGFIVNIHGKPSNKLLRDAQKISDRMEHRGATSGDNLTGDGAGVLASIPYEFYSKTVKETYNIILPEPGKYATGILFLDKITNTQVEEKFASIANENGLRIICWRTVPKNSSVIGEMARTQEPLMRQVFVESVETDIDDREFQRKLFALRKYSTHKLVKEGFRYYICSLSTKTIVYKGQFTPAQLWQYFDDLWDPEFRCYLALVHARFSTNTYPSWERAHPNRYLAHNGEINTLRGNINFMRAREGVMSSKYFGNKLSKLYPVVEPNMSDSGSLDNVLEFLVTVGGRTLPEAVMTMVPEAWQNDTEMHPEKKLFYQWSGCAMEPWDGPALLTFTDGRYIGAILDRNGLRPARFYQTEDGHVVMASEVGVVDFPNEEIIARGRLKPGRMLLIDTQEEIMVKDEEIKLTIARKRPLAEWLKELFTIEHLREAHTVSKLAKDGSFKRKAVLLEGRSEEEVETRAKVLEDRRLPLFAYTTETINLLLLPMVRTQKEALGSMGNDEPLACLSLYQPLIYGYFKQLFAQVTNPPIDPIREKIVMSLACPVGPEANILESSAEQCRRLWLKQPILSINDLEVIKQTNYKGWRTKVIECVFPVKDGRSGLRKRLDQIRREACDAARDGFTIIVLSDRMAGPQFVPVSMLLALGATHHYLINERQRMKVALFVESGEAREVHHMCVLLGYGADAICPYLVFETVAALREEGVIQLTDLEAFNNYFLSMERGIAKVMAKMGISTLHSYKGAQIFEAVGLGEEVIDFCFKNTPSRIGGVNFNILADEIVERHSIAFNKKYFIDQLILRNPGFYHWRNGGEKHINHPMAIANLQEAASLNSRHAYRKFVDFTKEQVKNCTLRGQMGFIYASKAVPLDEVEPVTMIVKRFVTGAMSFGSISYETHTTLAIAMNRVGAKSNTGEGGEDSERWLVKDPDQNKRSAIKQVASGRFGVTSAYIANADELQIKMAQGAKPGEGGELPGHKVSIEIAKTRHSVPGVGLISPPPHHDIYSIEDLSQLIYDLKCANPNARISVKLVSEVGVGIVAAGVAKGKAEHITISGHDGGTGASSWTGIKNAGLPWELGISETHQVLVANNLRSRVVLQADGQIRTAQDVITAALLGADEFGFSTAPLITLGCIMMRKCHLNTCPVGVATQDPELRKKFKGQPEHVINYLFLLAEEIREEMAKLGIRRFQNLIGRTELLRFTPNPRNPKASFLDYTLLLCNALSLRPETNIVGGSIRQDFELESRLDNKLIELSQEIIDGNFLQPIHIEMEISNRDRAFGATLSYNISRRYGEDGLPKNLIFVNLKGSAGQSFCLFLVKGVTVTLEGECNDYVGKGLSGGEIIIYPPKNSPPTFESDKNVIVGNVSLYGATSGRAFFRGIAAERFCVRNSGVTAVVEGVGDHGCEYMTGGIVVVLGLTGRNFAAGMSGGIAYVYDIDGRFNRRCNLEMVELLPMDEDEDIIKLQELIHEFWEKTDSKIAEHILNDWQKEMKKFVKVFPYEYQRVLKDMKLKKPLIPSRRASPATTPSDPPKDIEDIVPDLTKLDKLKGFMKYKRIKTYYRDTDKRIKEWDEVYDFKAIRENVRVQASRCMECGVPFCQSQHGCPLGNIIPRWNDLVHKNDWYEALKQLLQTNNFPEFTGRVCPAPCEGSCTLGIIDSPVAIKTIEVSIIEYAFEQGWIRSNSPKHRSGKKVAIIGSGPAGLACADQLNKAGHTVCVYERQDRIGGLLQYGIPTMKLSKKVLQRRIDLMTEAGIMFKPSTNVGIDITGQQLLEQYDAICLTTGATWPRDLRISGRELNGIYFAVDYLRSSQQKLWENSFDHPITAKDKNVIVIGGGDTGCDCIGTALRQGAKNVVAFEILPKPPKDRSGDNPWPQWPKIYRIDYGHEEAKLRWNDDPRIYEISSKKFIGDENGNVSGIDTVRVNWTKNEKGGWVMNEVVGTELTFKADLVLLAMGFLGPESTIIEQLNLTKDNRSNILTKPNSYRTPIERIYSAGDCRRGQSLVVHAIHEGRQAACEIDTDFSEKFNKSGLPGPGGIIPYEQCVVAH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ASGP02000004
EMBL· GenBank· DDBJ
KAH9511696.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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