A0A922HW88 · A0A922HW88_DERFA

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
    EC:3.4.19.12 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functioncysteine-type deubiquitinase activity
Biological Processprotein deubiquitination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ubiquitinyl hydrolase 1
  • EC number

Gene names

    • Name
      USP20
    • ORF names
      DERF_010067

Organism names

  • Taxonomic identifier
  • Strain
    • Derf
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides

Accessions

  • Primary accession
    A0A922HW88

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain16-555USP
Region82-108Disordered
Compositional bias784-800Acidic residues
Region784-839Disordered
Compositional bias807-827Acidic residues
Domain839-1101DUSP
Region1129-1172Disordered
Region1207-1256Disordered
Compositional bias1225-1245Polar residues

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,256
  • Mass (Da)
    147,486
  • Last updated
    2023-02-22 v1
  • Checksum
    76087EA560919C50
MNEEAEDFPQNIRGLKGLQNLGNTCYINATLQALLHIRPLRLYFTETYYRRLRLQWDNSIDSLFHQFMMTLWTMPSSSSSSLNNHHHHHQSKNHSSMNDTSTTTTASSSKNVNYAQDSLVILRALVSFIWKRYSFFSPGDQHDSQEFLQCLLGDLHDALKIPFYPESQFLHYKLRNCDYQLRKLAKYLIEHDFDCNEYDADHEYYKKIDEFIQQSRLVNYYHSKNYQPITSMDNQHDISIDHDGDHTDEPILYNLFNQNPSHNQDNDHNCNSNSNHGDHQHLKYRSIISDLFAGELENTIRCTNCGRTSILTETFLNLSIPITAIDRAIQSKIQNSMVFPNIRLSVPFNNQQQQQHQSATNQSSLIEKSLNYAFETIRFYYDYLWNWFDWFMSFLSNPSVDLMDCLETFFNPELLENENRYHCDNCKKLCNGIKCIRIKRLPEILIVHLNRYQNVNSVVRKITSQLTFPLNDFSLKSFLSETTTNVTYSADAQYDLVAVVCHNGTQVTNGHYICYALNEINLDWYEFDDTYVTYVSKDRILSMASSAYILFYQRVDPKSIMTRTMNIIYDIEHRWMESCTDNSYLKRLNLNLQDYYFFTTQSSSSSSSYKVNVDDAFINLKSVPLSKQWLMAFQSLQYPGPIDNSDIFCIHGLIRPTEYLFFNNLSLPVIEPVGQFLWLLYGGGPLFRCSGFIENRNNEQQQQQYAVCLQCSSLLDMYDERRKSEFNEFIQLQSMHVHMFRKLKLKTSELTIIIDKCNDQNHQDDGQVQQQQQSDQEDNLLIISNDDDDDDDDEDDEKKELDENGAIITTADDDDDDDDDNDDDGDGNENETNNKTKSKKSSIEMKMLDTMMMTIDDEQSAYYYLISAEWIIKWLSFVNVRFDQSTVTARDRQLFSHYEQIFKKQEERQQNPQPYDEQYHRMIYLRTKTIHPPLASLLRSIMNTMNKNQFQIDTEDMLKQIDLDLHTVLPPGPIDNWSIFGIKRKILTENRNRENMNNKDPLKQKSMTIDMATKYDDLCKLFAEILAGQSSANDFVSNNNVEYSSDNQTIKCQYRFAFHSRYGGLYEENSSCVFYLVSSDYWNLFSQTYGGGPTIRFNYLLNKFEANITVNDIEFFIREHYRSRQTMVNNNGDNDNNNDHDDGHSETENNDDDDDGNDDKNDQQQQQQKTEQIDLMQKQQNDEPVLIESLENNDILINNNDSHQTEIETNICRRRRRRRQQRQRRNNSGNNNNQPVKSSTTTAPETMNDDDHDKMD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias784-800Acidic residues
Compositional bias807-827Acidic residues
Compositional bias1225-1245Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ASGP02000004
EMBL· GenBank· DDBJ
KAH9511619.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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