A0A922HSZ9 · A0A922HSZ9_DERFA
- ProteindCTP pyrophosphatase 1
- GeneDCTPP1_2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids113 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
function
Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
Catalytic activity
- dCTP + H2O = dCMP + diphosphate + H+
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | dCTP diphosphatase activity | |
Molecular Function | magnesium ion binding | |
Biological Process | dCTP catabolic process | |
Biological Process | DNA protection |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedCTP pyrophosphatase 1
- EC number
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides
Accessions
- Primary accessionA0A922HSZ9
Proteomes
Subcellular Location
Interaction
Subunit
Homotetramer.
Structure
Sequence
- Sequence statusComplete
- Length113
- Mass (Da)13,373
- Last updated2023-02-22 v1
- Checksum2CB95812C3DA720D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
SDOV01000006 EMBL· GenBank· DDBJ | KAH7640159.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
ASGP02000005 EMBL· GenBank· DDBJ | KAH9506686.1 EMBL· GenBank· DDBJ | Genomic DNA |