A0A922HSZ9 · A0A922HSZ9_DERFA

Function

function

Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctiondCTP diphosphatase activity
Molecular Functionmagnesium ion binding
Biological ProcessdCTP catabolic process
Biological ProcessDNA protection

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dCTP pyrophosphatase 1
  • EC number

Gene names

    • Name
      DCTPP1_2
    • ORF names
      DERF_011405
      , HUG17_10639

Organism names

  • Taxonomic identifier
  • Strains
    • Derf
    • JKM2019
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides

Accessions

  • Primary accession
    A0A922HSZ9

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    113
  • Mass (Da)
    13,373
  • Last updated
    2023-02-22 v1
  • Checksum
    2CB95812C3DA720D
MDQSIDSNKIDKSFHFSPLTLEQIRQMHDDFVMKRNWEQFHQPRNILLALIGELGEIAENFQWKPDSYCDNGLTKWTEKERNALADELSDVLIYLIRLSDRCRIDVSKTICKN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SDOV01000006
EMBL· GenBank· DDBJ
KAH7640159.1
EMBL· GenBank· DDBJ
Genomic DNA
ASGP02000005
EMBL· GenBank· DDBJ
KAH9506686.1
EMBL· GenBank· DDBJ
Genomic DNA

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Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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