A0A922HGJ6 · A0A922HGJ6_DERFA

Function

function

Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

tRNA modification; N7-methylguanine-tRNA biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site79S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site102-103S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site135-136S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site155S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site158
Binding site232-234S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentnucleus
Cellular ComponenttRNA methyltransferase complex
Molecular FunctiontRNA (guanine(46)-N7)-methyltransferase activity
Molecular FunctiontRNA binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (guanine-N(7)-)-methyltransferase
  • EC number
  • Alternative names
    • tRNA (guanine(46)-N(7))-methyltransferase
    • tRNA(m7G46)-methyltransferase

Gene names

    • Name
      METTL1_1
    • ORF names
      DERF_014082

Organism names

  • Taxonomic identifier
  • Strain
    • Derf
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Acariformes > Sarcoptiformes > Astigmata > Psoroptidia > Analgoidea > Pyroglyphidae > Dermatophagoidinae > Dermatophagoides

Accessions

  • Primary accession
    A0A922HGJ6

Proteomes

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-22Disordered

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    263
  • Mass (Da)
    30,950
  • Last updated
    2023-02-22 v1
  • Checksum
    1773F39890A7335C
MTEYSTSIEQKPPPESSSSSLSVCLPQKRYYRQRAHSNPIADHFFDDYPITPDDVDWSSFYPLYMNNENGSKVEFLDIGCGYGGLLIELSSLYPESLMLGIEIRQKVSDYVVERIRALRVQNPGKYNNINCIRSNAMKYMPNFFNKSQLSKIFFLFPDPHFKKQKHKWRIISPQLLTEYAYFLRIDGRAYFASDVKELFDWMYKHFDDHPLFIQVQDSDNDDDPVVKKFTLTEEGKKVTRNGGQIWHAVFRRIDDPKDQHNKD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ASGP02000008
EMBL· GenBank· DDBJ
KAH9493326.1
EMBL· GenBank· DDBJ
Genomic DNA
ASGP02000008
EMBL· GenBank· DDBJ
KAH9493327.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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