A0A921NCW7 · A0A921NCW7_9BACL

Function

function

Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), the presumed physiological substrate. Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FMN (UniProtKB | Rhea| CHEBI:58210 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site56Zn2+ (UniProtKB | ChEBI); catalytic
Active site58Proton donor
Binding site86Zn2+ (UniProtKB | ChEBI); catalytic
Binding site89Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Molecular Functionnitronate monooxygenase activity
Molecular FunctiontRNA-specific adenosine-34 deaminase activity
Molecular Functionzinc ion binding
Biological Processresponse to toxic substance
Biological ProcesstRNA wobble adenosine to inosine editing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-specific adenosine deaminase
  • EC number

Gene names

    • Name
      tadA
    • ORF names
      K8V30_05905

Organism names

  • Taxonomic identifier
  • Strain
    • CHK160-4876
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Planococcaceae > Metalysinibacillus

Accessions

  • Primary accession
    A0A921NCW7

Proteomes

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-114CMP/dCMP-type deaminase

Sequence similarities

Belongs to the nitronate monooxygenase family. NMO class I subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    483
  • Mass (Da)
    53,023
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    D4FCE41CB08DBDE1F25555A972EC1A23
MRDFSKDAYFMQLALDEAKQAARLGEVPIGAIIVYKDQVIANTHNLCETTQNPTAHAELLAIEQACRYLDDWRLEETTLYVTLEPCPMCAGAILQARIPRVVYGAKDDKAGCVHSLYELLNDERFNHQCRVTQGVLAPQCKQILQHFFAEVRAQNKRRKRMQTIIQAPMAGVSTPAFVIAAHEAGILGSFGAGYLTAEQTKLAIDEIKKVTSRFVVNVFVPENIAFTTAQMEEAYRAIRPFERQLNLHEQPLPEVQQHFHSQLEVILEAGISHVSFTFGIPPAIWIERFKKRGVTLIGTATTVEEAIVNERAGMDMIVVQGIEAGGHRGTFLTGEQLPLKQLLKNVGRAVNIPLIAAGGIATKAHIDYYLAKGASAVQIGTALLATDESGASLIHKQTLLANTQDTTVLTRAFSGKTARGITNTFIQEMACAPIAPYPAQHFLTARLRSESAKQHNAQFVSMWSGVNGHLAQAGSLKSVIETL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DYTV01000074
EMBL· GenBank· DDBJ
HJH11218.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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