A0A921MTP8 · A0A921MTP8_9MICO

Function

function

Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site855-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site85anthranilate 1 (UniProtKB | ChEBI)
Binding site88-895-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site935-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site95-985-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site97Mg2+ 1 (UniProtKB | ChEBI)
Binding site113-1215-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site116anthranilate 1 (UniProtKB | ChEBI)
Binding site1255-phospho-alpha-D-ribose 1-diphosphate (UniProtKB | ChEBI)
Binding site171anthranilate 2 (UniProtKB | ChEBI)
Binding site229Mg2+ 2 (UniProtKB | ChEBI)
Binding site230Mg2+ 2 (UniProtKB | ChEBI)
Binding site230Mg2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionanthranilate phosphoribosyltransferase activity
Molecular Functionmagnesium ion binding
Biological Processtryptophan biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Anthranilate phosphoribosyltransferase
  • EC number

Gene names

    • Name
      trpD
    • ORF names
      K8V81_02645

Organism names

  • Taxonomic identifier
  • Strain
    • ChiGjej5B5-22894
  • Taxonomic lineage
    Bacteria > Bacillati > Actinomycetota > Actinomycetes > Micrococcales > Dermabacteraceae > Brachybacterium

Accessions

  • Primary accession
    A0A921MTP8

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain11-71Glycosyl transferase family 3 N-terminal
Domain79-339Glycosyl transferase family 3

Sequence similarities

Belongs to the anthranilate phosphoribosyltransferase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    360
  • Mass (Da)
    37,158
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    4BAA031E815E45218697556849985169
MNDNIPTWSRITAQLVRGEELDGGAAAWAMDEVMSGNASAVQLAGFLVSLQSKGVTSTELEALADSMIAHARPLDAPREAIDIVGTGGDLAQTVNISTMASVVIAATGRTVVKHGNRASTSRSGSADVLEALGIRLDLPVPEVEALVERVGMTFLFAQVFHPSMKYAAEARRGLGIPTVMNILGPITNPARPRASAVGVADPSIAPTVAGVFASRGTSALVFRGQDGLDELTVTAPSDVWEVRGGEIAQHVLDPAVLVEVPRSGHDALRGGTAEENAQVARDLYAGESSGRMGPIRDAVLLNAAAGVVAFDGIGQSAGAGFEGRFVAAFEEVRAALDSGAPADLIGRWAAASQEAFARQS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DYUE01000072
EMBL· GenBank· DDBJ
HJG90603.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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