A0A918YYN9 · A0A918YYN9_9GAMM

  • Protein
    Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
  • Gene
    wecA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site153Mg2+ (UniProtKB | ChEBI)
Binding site218Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentGram-negative-bacterium-type cell wall
Cellular Componentplasma membrane
Molecular Functionglycosyltransferase activity
Molecular Functionisomerase activity
Molecular Functionmagnesium ion binding
Molecular Functionmanganese ion binding
Molecular FunctionUDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity
Biological Processcell wall macromolecule biosynthetic process
Biological Processcell wall organization
Biological ProcessO antigen biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
  • EC number
  • Alternative names
    • UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase
    • Undecaprenyl-phosphate GlcNAc-1-phosphate transferase

Gene names

    • Name
      wecA
    • ORF names
      GCM10007167_08790

Organism names

  • Taxonomic identifier
  • Strain
    • KCTC 32020
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Lysobacterales > Lysobacteraceae > Vulcaniibacterium

Accessions

  • Primary accession
    A0A918YYN9

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein
Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-24Helical
Transmembrane45-66Helical
Transmembrane72-89Helical
Transmembrane101-119Helical
Transmembrane131-151Helical
Transmembrane158-177Helical
Transmembrane183-203Helical
Transmembrane215-236Helical
Transmembrane294-313Helical
Transmembrane319-340Helical

Keywords

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region360-379Disordered
Domain400-739UDP-N-acetylglucosamine 2-epimerase

Sequence similarities

Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
Belongs to the glycosyltransferase 4 family. WecA subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    770
  • Mass (Da)
    81,554
  • Last updated
    2023-02-22 v1
  • Checksum
    F10582B01911C2E4
MDDAKLEAASAIALAVTLFLIFTVRPLARRFGLVDKPNERKRHRGSVPLIGGLCFFLGTVVGLAYAGYVDRTIATLMIPSGLIVMVGVLDDLFDLSVRLRLAVQAAAAVMVIAASGLYLDHAGRLFGDAPFALGALGIPLSVIAVIGLINAFNMLDGIDGLAASIAMVAIAAIFLYSGGSAGAMTGVLLLLQVLFAALVPYLCVNLGWPDGRKVFMGDAGSTLIGFLLAWSLIFMSHSSVDRLAPVDALWVVAVPVMDTLGVMYRRARRGVSVFKPDRQHLHHLLQDAGLTPRMALAVIVAMAVTLVAVGYVLRAVPDLLNLTLFLAVLASYVLLFQTALERARLLVRGRHGLQAGEPTLAAASGNEPAPPAREPSTPPLRALCVAGSSPETLQLAPIVRELEQDGRFDARFCVAAPDPGEQERVLGLFGIRPDARIELPPSAAHGAIDAETMNGMKRLLGEFRPDVVLVPGDSPATLAASLAAFSQRIPIARIESALPDEARGARADAVSRRLSSLLATVNIAPSECRGRRLLDTGIPAERIVLAPNAASASLRAAVRRIDADPELRAALAQTFSHLREGHPLLLVSCCGRLIETFTPLYRSLARIAAQRPDLDIVCALDDPDHLRADALRRDFSNVHLIAPRDYLAFACLLERASVILAASTEVAQDVAPLGKPVLLLQRDDAGVAVDAANVMPVRAERDGIAASVLTLLSDPVAYERMCLPEPAGEDACRRVVETLASLRPAADPTPAESWAGLPVAPIVQGVSGSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BNCF01000003
EMBL· GenBank· DDBJ
GHE29212.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp