A0A918MYL6 · A0A918MYL6_9BURK

  • Protein
    Peroxisomal trans-2-enoyl-CoA reductase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    3/5

Function

function

Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • (2E)-decenoyl-CoA + H+ + NADPH = decanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-dodecenoyl-CoA + H+ + NADPH = dodecanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-hexenoyl-CoA + H+ + NADPH = hexanoyl-CoA + NADP+
    This reaction proceeds in the forward direction.
  • (2E)-octenoyl-CoA + H+ + NADPH = NADP+ + octanoyl-CoA
    This reaction proceeds in the forward direction.
  • (2E)-tetradecenoyl-CoA + H+ + NADPH = NADP+ + tetradecanoyl-CoA
    This reaction proceeds in the forward direction.
  • a (2E)-enoyl-CoA + H+ + NADPH = a 2,3-saturated acyl-CoA + NADP+
    This reaction proceeds in the forward direction.
    EC:1.3.1.38 (UniProtKB | ENZYME | Rhea)

Pathway

Lipid metabolism.

GO annotations

AspectTerm
Cellular Componentperoxisome
Molecular Functiontrans-2-enoyl-CoA reductase (NADPH) activity
Biological Processphytol metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Peroxisomal trans-2-enoyl-CoA reductase
  • EC number

Gene names

    • ORF names
      GCM10011450_14560

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KCTC 23732
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Alcaligenaceae

Accessions

  • Primary accession
    A0A918MYL6

Proteomes

Subcellular Location

PTM/Processing

Keywords

Interaction

Subunit

Interacts with PEX5, probably required to target it into peroxisomes.

Family & Domains

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    90
  • Mass (Da)
    9,589
  • Last updated
    2023-02-22 v1
  • Checksum
    38F88667FB2840FA
MELGETGVRVNCVSPGAIDNGQRAIPRNANPLSAQEQEWMKGIYTQSLRDTPMNRLGQMEEIAAAICFFAAPEASYVTGQVLYVAGGGIG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BMYS01000008
EMBL· GenBank· DDBJ
GGW85646.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp