A0A917RMT9 · A0A917RMT9_9NOCA
- ProteinPeroxisomal trans-2-enoyl-CoA reductase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids154 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2,4-dienoyl-CoA reductase activity.
Catalytic activity
- (2E)-decenoyl-CoA + H+ + NADPH = decanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-dodecenoyl-CoA + H+ + NADPH = dodecanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-hexenoyl-CoA + H+ + NADPH = hexanoyl-CoA + NADP+This reaction proceeds in the forward direction.
- (2E)-octenoyl-CoA + H+ + NADPH = NADP+ + octanoyl-CoAThis reaction proceeds in the forward direction.
- (2E)-tetradecenoyl-CoA + H+ + NADPH = NADP+ + tetradecanoyl-CoAThis reaction proceeds in the forward direction.
Pathway
Lipid metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Biological Process | lipid metabolic process |
Keywords
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePeroxisomal trans-2-enoyl-CoA reductase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Nocardiaceae > Nocardia
Accessions
- Primary accessionA0A917RMT9
Proteomes
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-22 | |||||
Sequence: MLSTLTTWIWTGSAFVVPSAMA | ||||||
Chain | PRO_5039301063 | 23-154 | Peroxisomal trans-2-enoyl-CoA reductase | |||
Sequence: KAAVHAMTMSLAVEWARHGIRLNAIAAGPIPTDYAWEMLNPTEKSSVGATQPDQIPMGRTGTVEELADLTIFLLSDACEYLTGQTIAMDGGQMLAGPGTFAGLTSMSEQDWARAREHSKAASEAAKAQRATL |
Keywords
- PTM
Interaction
Subunit
Interacts with PEX5, probably required to target it into peroxisomes.
Structure
Sequence
- Sequence statusComplete
- Length154
- Mass (Da)16,358
- Last updated2023-02-22 v1
- Checksum69320AE59A3342FA
Keywords
- Technical term