A0A915U076 · A0A915U076_9BACT

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

129120406080100120140160180200220240260280
Type
IDPosition(s)Description
Active site53Proton acceptor
Binding site53-54NAD+ (UniProtKB | ChEBI)
Binding site58NAD+ (UniProtKB | ChEBI)
Binding site129-130NAD+ (UniProtKB | ChEBI)
Binding site140NAD+ (UniProtKB | ChEBI)
Binding site157NAD+ (UniProtKB | ChEBI)
Binding site159NAD+ (UniProtKB | ChEBI)
Binding site170-175NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      nadK
    • ORF names
      GF1_07460

Organism names

Accessions

  • Primary accession
    A0A915U076

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    291
  • Mass (Da)
    31,857
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    91DFAB00B5F1BDF5E3AC980071FBB25D
MKKDFVGIITKRDAPDVHQVGTELATWLEQWGIRAALDRIDPAMDMLVILGGDGTLLHVAAQASHLDIPVVGINLGNLGFLTEVAAGEMYQALETILAGKARIEKRMMLRASLFSGRDGQESEPLFALNEVVIVKESTDRIMRLSSWADEEFITTYKGDGLIISTPTGSTAYNLSAGGPIVHAELGTILVTPICPFMLESRPVLLSPDVRITTRLADPENDVKVIVDGRPGWDMKAEDCLVVQAAAKPLRLISSPHKGYFAILRNKLNWGGRDEGFPLPDMVRKNRRDSGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP024233
EMBL· GenBank· DDBJ
BCO08370.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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