A0A915U076 · A0A915U076_9BACT
- ProteinNAD kinase
- GenenadK
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids291 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
Catalytic activity
- NAD+ + ATP = ADP + NADP+ + H+
Cofactor
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 53 | Proton acceptor | |||
Binding site | 53-54 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 58 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 129-130 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 140 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 157 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 159 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 170-175 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | NAD binding | |
Molecular Function | NAD+ kinase activity | |
Biological Process | NAD metabolic process | |
Biological Process | NADP biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD kinase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfobulbia > Desulfobulbales > Desulfobulbaceae > Desulfolithobacter
Accessions
- Primary accessionA0A915U076
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length291
- Mass (Da)31,857
- Last updated2023-02-22 v1
- MD5 Checksum91DFAB00B5F1BDF5E3AC980071FBB25D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP024233 EMBL· GenBank· DDBJ | BCO08370.1 EMBL· GenBank· DDBJ | Genomic DNA |