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A0A915CKU6 · A0A915CKU6_PARUN

Function

Cofactor

Protein has several cofactor binding sites:
Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Can bind about 5 Ca2+ ions per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site, active site.

153850100150200250300350400450500
Type
IDPosition(s)Description
Binding site81Zn2+ 2 (UniProtKB | ChEBI); catalytic; in inhibited form
Binding site157Ca2+ 2 (UniProtKB | ChEBI)
Binding site167Zn2+ 1 (UniProtKB | ChEBI)
Binding site169Zn2+ 1 (UniProtKB | ChEBI)
Binding site174Ca2+ 3 (UniProtKB | ChEBI)
Binding site175Ca2+ 3 (UniProtKB | ChEBI)
Binding site182Zn2+ 1 (UniProtKB | ChEBI)
Binding site191Ca2+ 2 (UniProtKB | ChEBI)
Binding site193Ca2+ 2 (UniProtKB | ChEBI)
Binding site195Zn2+ 1 (UniProtKB | ChEBI)
Binding site197Ca2+ 3 (UniProtKB | ChEBI)
Binding site198Ca2+ 1 (UniProtKB | ChEBI)
Binding site200Ca2+ 1 (UniProtKB | ChEBI)
Binding site200Ca2+ 3 (UniProtKB | ChEBI)
Binding site223Zn2+ 2 (UniProtKB | ChEBI); catalytic
Active site224
Binding site227Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site233Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site241Zn2+ 2 (UniProtKB | ChEBI); catalytic
Binding site324Ca2+ 4 (UniProtKB | ChEBI)
Binding site326Ca2+ 5 (UniProtKB | ChEBI)
Binding site369Ca2+ 4 (UniProtKB | ChEBI)
Binding site371Ca2+ 5 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentextracellular matrix
Cellular Componentextracellular space
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processcollagen catabolic process
Biological Processextracellular matrix organization
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Peptidase metallopeptidase domain-containing protein

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Spirurina > Ascaridomorpha > Ascaridoidea > Ascarididae > Parascaris

Accessions

  • Primary accession
    A0A915CKU6

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-18
ChainPRO_504118996219-538

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias, repeat.

Type
IDPosition(s)Description
Domain102-267Peptidase metallopeptidase
Region270-317Disordered
Compositional bias286-302Pro residues
Repeat320-364Hemopexin
Repeat365-412Hemopexin
Repeat460-504Hemopexin

Sequence similarities

Belongs to the peptidase M10A family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    538
  • Mass (Da)
    61,007
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    160D6046F84701421588B5E671542A24
MLLLIFTFVSALLVTSLGTYSSKTLRYLEEFGYLPKPSGAAAMLSKTVVEEAIRELQLYGNVPVTGKIDAATRELMTRKRCGLPDRQTKLHRMRHRKRYVLMGPIWDKKLLTYSVDNPSRSMPYVGDVRREVSEAIDAWQRASALRLKEVRSEADADIRIRFAVGDHGDPYFFDGTGRILAHAFPPGEGLGGDVHLDDDERWTNALTGDPHSQQVSLRSIVMHEIGHSLGLSHSQQEDSIMYSFYQYDLAPELSYDDVLAVQSIYGRGRAPAPRRPNLLPTTTTTHLPPLPSPSPRPPSRHPDIPTNTDNGELIAPDPCTSDVDAITEIRGEVFAFKGDWFWRIHHDGYLSEGPRLISSFWQSLPSPVDAAVEDNDKILFFVGRNVYVYSGHKQEAVKPLTALGLPEYVDHIRLVYTWNYWTEKPIYIWTDDEFWRVDKSSGKVEVGYPRKIITTWHYVPPEASAAFTFNDDLYFFAGTDVLKFHSINMSATERQPSSQIWRHCPTAMRISSQSASYFPFHFTYLLQTVTLALFAAVI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias286-302Pro residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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