A0A914L2H5 · A0A914L2H5_MELIC
- Protein4-trimethylaminobutyraldehyde dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids187 (go to sequence)
- Protein existencePredicted
- Annotation score4/5
Function
function
Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines.
Catalytic activity
- (5-hydroxyindol-3-yl)acetaldehyde + NAD+ + H2O = (5-hydroxyindol-3-yl)acetate + NADH + 2 H+
- 3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O = 3,4-dihydroxyphenylacetate + NADH + 2 H+
- pentanal + NAD+ + H2O = pentanoate + NADH + 2 H+
- propanal + NAD+ + H2O = propanoate + NADH + 2 H+
- spermine monoaldehyde + NAD+ + H2O = N-(2-carboxyethyl)spermidine + NADH + 2 H+
- hexanal + NAD+ + H2O = hexanoate + NADH + 2 H+
- imidazole-4-acetaldehyde + NAD+ + H2O = imidazole-4-acetate + NADH + 2 H+
- acrolein + NAD+ + H2O = acrylate + NADH + 2 H+
- butanal + NAD+ + H2O = butanoate + NADH + 2 H+
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4-trimethylammoniobutyraldehyde dehydrogenase activity | |
Molecular Function | aminobutyraldehyde dehydrogenase (NAD+) activity |
Keywords
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name4-trimethylaminobutyraldehyde dehydrogenase
- EC number
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Tylenchina > Tylenchomorpha > Tylenchoidea > Meloidogynidae > Meloidogyninae > Meloidogyne > Meloidogyne incognita group
Accessions
- Primary accessionA0A914L2H5
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 29-164 | Aldehyde dehydrogenase | ||||
Sequence: LFKIIEPRNGNLLAECKSATGPDITLAVRVASGAQKEWGKTSWIDRQQILNRTAILLREHVNELSGWEVRDNGKPISEAKADILSCADTFEYFAGVRLAGEHFPYDEQNERFAYTRREPYGVVGAIGAWNYPIQTP |
Family and domain databases
Sequence
- Sequence statusComplete
- Length187
- Mass (Da)21,069
- Last updated2023-02-22 v1
- Checksum77E9DD29F581A816
Keywords
- Technical term