A0A8X8RMJ2 · A0A8X8RMJ2_9CAUD

  • Protein
    NAD(+)--arginine ADP-ribosyltransferase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

ADP-ribosyltransferase that efficiently ADP-ribosylates one of the two alpha subunits of host RNA polymerase RPOA on an arginine located in the C-terminal region. ADP-ribosylation of RPOA alpha subunit enhances the transcription of viral early genes. Also ribosylates RPOA subunits beta, beta' and sigma 70 and performs an autoribosylation reaction.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for site, active site.

168550100150200250300350400450500550600650
TypeIDPosition(s)Description
Site6-7Cleavage
Active site589

GO annotations

AspectTerm
Cellular Componentextracellular region
Cellular Componentvirion component
Molecular FunctionNAD+-protein-arginine ADP-ribosyltransferase activity
Molecular Functionnucleotidyltransferase activity
Biological Processregulation of viral transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD(+)--arginine ADP-ribosyltransferase
  • EC number

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Tevenvirinae > Tequatrovirus

Accessions

  • Primary accession
    A0A8X8RMJ2

Proteomes

Subcellular Location

Virion
Note: About 25-50 copies per virion. This protein is injected into the bacterial cell along with the viral DNA.

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_50423009031-685NAD+--arginine ADP-ribosyltransferase

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain416-620ADP ribosyltransferase

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    685
  • Mass (Da)
    75,860
  • Last updated
    2022-12-14 v1
  • Checksum
    8644818614350F77
MELITELFDGASAPVVNLNPKHKIPQIFAIQAGEESVLPGFRFCTYTSGGDTNKNVKPGDKMMHIVMIGVNEKLSLVKLKNLGGNPIGVINAVFDTALQTMKQYKIDACLFRVLKSKTNGAARQMQVIADRLVRTKGAGRYVLLKEIWDYDKKYAYIMVYRKNANLEDIPGVPPISTELFTKVESKVGDVYVDVKTGNAVPKAVAVAASIALENDKRTDQAVIQKTKISRRLAAQAQYSTVDASLQGDSFAAKKYQELESKVPVYKAEGPMNSGVIQIGSNFGKGAIGGMRSASRFKSNDYELESFRNHIALAHARLRDPSIKLQSDTTYQGSQEYLKNKEFFDYKTDKILSDLADINISNSFDVIKKIINDLVKGSKATPDEKTAIIQFVMNGIYKLINESAAQAYEYASTEVTPKGLTQAESDVIEDYCADSYVEMNSFLLGKPDSTREEYMERAIKHIETLDSAFAKGSVLPPGTTLYRGQEVTFKTLRHNIENKMFYFKNFVSTSLKPNIFGEHGKNYMALDDSGAVFSGEGEGSVDAEDLMHMGSHSTYANEDAETSVGMVIKGAERIKVIVPGHLSGFPSEAEVILPRGILLKINKVSTYMMKETAYNKYLIEGTIVPPSEQLEESVYDGDHLMETGEVRPMAGFNQFLVEESKEEENEVSQILASLVNINGMSKKFKM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ON528739
EMBL· GenBank· DDBJ
URY14378.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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