A0A8X8MBC0 · A0A8X8MBC0_9CAUD

  • Protein
    NAD--protein ADP-ribosyltransferase modA
  • Gene
    modA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

ADP-ribosyltransferase that efficiently ADP-ribosylates both alpha subunits of host RNA polymerase RPOA. The ModA-induced ADP-ribosylation of RPOA alpha subunits inhibits transcription from viral early promoters.

Catalytic activity

Features

Showing features for binding site, active site.

120020406080100120140160180200
TypeIDPosition(s)Description
Binding site72NAD+ (UniProtKB | ChEBI)
Active site165

GO annotations

AspectTerm
Cellular Componentvirion component
Molecular FunctionNAD+-protein-arginine ADP-ribosyltransferase activity
Molecular Functionnucleotidyltransferase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD--protein ADP-ribosyltransferase modA
  • EC number
  • Alternative names
    • RNA polymerase ADP-ribosylase modA

Gene names

    • Name
      modA

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Tevenvirinae > Tequatrovirus

Accessions

  • Primary accession
    A0A8X8MBC0

Proteomes

Subcellular Location

Virion
Note: This protein is injected from the virion into the bacterial cell.

Keywords

  • Cellular component

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    200
  • Mass (Da)
    23,326
  • Last updated
    2022-12-14 v1
  • Checksum
    B36C890F806995DC
MKYSAMQLKDFKIKSMDASVRASIREELLSEGFNLSEIELLIHCITNKPDDHSWLNEIIKSRLVPNDKPLWRGVPVETKQVLNQGIDIITFDKVVSASYDKNIALHFASGLEYNTQVIFEFKAPMVFNFQEYAIKALRCKEYSPSFKFPDSHRYRNMELVSDEQEVMIPAGSVFKIADRYEYKKYSTYTIYTLDFEGFNL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ON528736
EMBL· GenBank· DDBJ
URY13573.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp