A0A8X8MAN1 · A0A8X8MAN1_9CAUD

  • Protein
    RNA polymerase sigma-like factor
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Plays a role in the transcription of the viral late genes by acting as a late promoter recognition subunit. Associates with host RNA polymerase (RNAP) core and thus replaces the host sigma-70/rpoD subunit in the complex. May also play a role in DNA packaging by interacting with the terminase subunit gp17.

Features

Showing features for site, dna binding.

118520406080100120140160180
TypeIDPosition(s)Description
Site70Interaction with host RNAP
Site74Interaction with host RNAP
Site77Interaction with host RNAP
DNA binding114

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionDNA binding
Molecular Functionnucleotidyltransferase activity
Molecular Functionsigma factor activity
Biological Processlate viral transcription

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    RNA polymerase sigma-like factor
  • Alternative names
    • Promoter specificity factor

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Viruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Tevenvirinae > Tequatrovirus

Accessions

  • Primary accession
    A0A8X8MAN1

Proteomes

Interaction

Subunit

Interacts with the host RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ to form the RNAP-gp55 holoenzyme. Part of the transcription activation complex containing host RNAP, the viral RNA polymerase sigma-like factor, the late transcription coactivator, and the sliding clamp. Interacts with the terminase large subunit; this interaction may load the terminase onto DNA for packaging.

Structure

3D structure databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region13-113Interaction with host RNAP core and recognition of the promoter specific element

Sequence similarities

Belongs to the Tevenvirinae RNA polymerase sigma-like factor family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    185
  • Mass (Da)
    21,536
  • Last updated
    2022-12-14 v1
  • Checksum
    C516CD13A63963D4
MSETKPKYNYVNNKELLQAIIDWKTELANNKDPNKVVRQNDTIGLAIMLIAEGLSKRFNFSGYTQSWKQEMIADGIEASIKGLHNFDETKYKNPHAYITQACFNAFVQRIKKERKEVAKKYSYFVHNVYDSRDDDMVALVDETFIQDIYDKMTHYEESTYRTPGAEKKSVVDDSPSLDFLYEAND

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ON528736
EMBL· GenBank· DDBJ
URY13621.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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