A0A8X7X0X7 · A0A8X7X0X7_POLSE
- ProteinPlasma membrane ascorbate-dependent reductase CYBRD1
- GeneCybrd1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids277 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- Cu2+(out) + L-ascorbate(in) = Cu+(out) + monodehydro-L-ascorbate radical(in) + H+This reaction proceeds in the forward direction.Cu2+ (out)CHEBI:29036
+ L-ascorbate (in)CHEBI:38290= Cu+ (out)CHEBI:49552+ CHEBI:59513 + CHEBI:15378 - monodehydro-L-ascorbate radical(out) + L-ascorbate(in) = monodehydro-L-ascorbate radical(in) + L-ascorbate(out)This reaction proceeds in the forward direction.
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | lysosomal membrane | |
Molecular Function | metal ion binding | |
Molecular Function | oxidoreductase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePlasma membrane ascorbate-dependent reductase CYBRD1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Polypteriformes > Polypteridae > Polypterus
Accessions
- Primary accessionA0A8X7X0X7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 7-30 | Helical | ||||
Sequence: FLLLLALSVLIGFVSVLFVLVWVF | ||||||
Transmembrane | 50-71 | Helical | ||||
Sequence: VLAVTGFIFIQGIAIVVYRLPW | ||||||
Transmembrane | 83-105 | Helical | ||||
Sequence: IHAGLNALAFTLMVISAVAVFDF | ||||||
Transmembrane | 117-142 | Helical | ||||
Sequence: LHSWIGLSVVILHSIQLLLGVCIYLL | ||||||
Transmembrane | 154-176 | Helical | ||||
Sequence: MPLHVYSGIFIFGAAIATALMGI | ||||||
Transmembrane | 196-217 | Helical | ||||
Sequence: AVFVNMLGIFIVVYGALILWMV |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 13-218 | Cytochrome b561 | ||||
Sequence: LSVLIGFVSVLFVLVWVFKWREGLGWDGGAAEFNWHPVLAVTGFIFIQGIAIVVYRLPWTWRCSKPMMKSIHAGLNALAFTLMVISAVAVFDFHNAKSIPNMYSLHSWIGLSVVILHSIQLLLGVCIYLLPSAPAFIRTAAMPLHVYSGIFIFGAAIATALMGITEKLIFSLKEPPYKNSPAEAVFVNMLGIFIVVYGALILWMVT | ||||||
Region | 225-245 | Disordered | ||||
Sequence: PGEQTSATRESGANEEDSTMA |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length277
- Mass (Da)30,751
- Last updated2022-12-14 v1
- ChecksumAFEED7E6B570D2AF
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: M | ||||||
Non-terminal residue | 277 | |||||
Sequence: M |
Keywords
- Technical term