A0A8V8TRB3 · A0A8V8TRB3_HUMAN
- ProteinSerine/threonine-protein phosphatase
- GenePPP2CA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids317 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chromosome, centromeric region | |
Cellular Component | nucleus | |
Cellular Component | spindle pole | |
Molecular Function | protein serine/threonine phosphatase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein phosphatase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A8V8TRB3
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 113 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Features
Showing features for modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Modified residue (large scale data) | 43 | PRIDE | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 114-119 | Serine/threonine specific protein phosphatases | ||||
Sequence: LRGNHE |
Sequence similarities
Belongs to the PPP phosphatase family. PP-1 subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length317
- Mass (Da)36,516
- Last updated2022-12-14 v1
- Checksum937F5FB18A179059
Computationally mapped potential isoform sequences
There are 6 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P67775 | PP2AA_HUMAN | PPP2CA | 309 | ||
E7ESG8 | E7ESG8_HUMAN | PPP2CA | 145 | ||
A0A8V8TRA6 | A0A8V8TRA6_HUMAN | PPP2CA | 181 | ||
A0A8V8TQA1 | A0A8V8TQA1_HUMAN | PPP2CA | 252 | ||
A0A8V8TQU8 | A0A8V8TQU8_HUMAN | PPP2CA | 239 | ||
B3KQ51 | B3KQ51_HUMAN | PPP2CA | 244 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC104109 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |