A0A8V8TRB3 · A0A8V8TRB3_HUMAN

  • Protein
    Serine/threonine-protein phosphatase
  • Gene
    PPP2CA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

GO annotations

AspectTerm
Cellular Componentchromosome, centromeric region
Cellular Componentnucleus
Cellular Componentspindle pole
Molecular Functionprotein serine/threonine phosphatase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein phosphatase
  • EC number

Gene names

    • Name
      PPP2CA

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A8V8TRB3

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Disease & Variants

Variants

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The viewer provides 113 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)43PRIDEPhosphoserine

Keywords

Proteomic databases

Structure

3D structure databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain114-119Serine/threonine specific protein phosphatases

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    317
  • Mass (Da)
    36,516
  • Last updated
    2022-12-14 v1
  • Checksum
    937F5FB18A179059
MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEIFVSFSLQGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL

Computationally mapped potential isoform sequences

There are 6 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P67775PP2AA_HUMANPPP2CA309
E7ESG8E7ESG8_HUMANPPP2CA145
A0A8V8TRA6A0A8V8TRA6_HUMANPPP2CA181
A0A8V8TQA1A0A8V8TQA1_HUMANPPP2CA252
A0A8V8TQU8A0A8V8TQU8_HUMANPPP2CA239
B3KQ51B3KQ51_HUMANPPP2CA244

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC104109
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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