A0A8V8TN99 · A0A8V8TN99_HUMAN
- ProteinHPS1 biogenesis of lysosomal organelles complex 3 subunit 1
- GeneHPS1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids663 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Biological Process | vesicle-mediated transport |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A8V8TN99
Proteomes
Organism-specific databases
Disease & Variants
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 756 variants from UniProt as well as other sources including ClinVar and dbSNP.
Genetic variation databases
PTM/Processing
Proteomic databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 2-159 | FUZ/MON1/HPS1 first Longin | |||
Domain | 205-403 | FUZ/MON1/HPS1 second Longin | |||
Region | 249-293 | Disordered | |||
Compositional bias | 260-293 | Polar residues | |||
Domain | 540-632 | FUZ/MON1/HPS1 third Longin | |||
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length663
- Mass (Da)75,109
- Last updated2022-12-14 v1
- Checksum4FF4D8C2D10A8D61
Computationally mapped potential isoform sequences
There are 17 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q92902 | HPS1_HUMAN | HPS1 | 700 | ||
A0A0S2Z4H4 | A0A0S2Z4H4_HUMAN | HPS1 | 132 | ||
H0Y4K4 | H0Y4K4_HUMAN | HPS1 | 291 | ||
A0A8V8TPI6 | A0A8V8TPI6_HUMAN | HPS1 | 710 | ||
A0A8V8TPJ1 | A0A8V8TPJ1_HUMAN | HPS1 | 786 | ||
A0A8V8TP54 | A0A8V8TP54_HUMAN | HPS1 | 377 | ||
A0A8V8TMS4 | A0A8V8TMS4_HUMAN | HPS1 | 140 | ||
A0A8V8TP59 | A0A8V8TP59_HUMAN | HPS1 | 509 | ||
A0A8V8TP64 | A0A8V8TP64_HUMAN | HPS1 | 644 | ||
A0A8V8TP71 | A0A8V8TP71_HUMAN | HPS1 | 194 | ||
A0A8V8TN79 | A0A8V8TN79_HUMAN | HPS1 | 571 | ||
A0A8V8TN86 | A0A8V8TN86_HUMAN | HPS1 | 122 | ||
A0A8V8TN90 | A0A8V8TN90_HUMAN | HPS1 | 611 | ||
A0A8V8TN94 | A0A8V8TN94_HUMAN | HPS1 | 613 | ||
A0A8V8TMQ9 | A0A8V8TMQ9_HUMAN | HPS1 | 580 | ||
A0A8V8TMR7 | A0A8V8TMR7_HUMAN | HPS1 | 74 | ||
A0A8V8TMR9 | A0A8V8TMR9_HUMAN | HPS1 | 136 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 260-293 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL139243 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |