A0A8V8TLR1 · A0A8V8TLR1_HUMAN
- ProteinXaa-Pro dipeptidase
- GenePEPD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids507 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- Xaa-L-Pro dipeptide + H2O = an L-alpha-amino acid + L-proline
Cofactor
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | manganese ion binding | |
Molecular Function | metalloaminopeptidase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameXaa-Pro dipeptidase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionA0A8V8TLR1
Proteomes
Organism-specific databases
PTM/Processing
Proteomic databases
Interaction
Subunit
Homodimer.
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 32-169 | Aminopeptidase P N-terminal | |||
Sequence similarities
Belongs to the peptidase M24B family. Eukaryotic-type prolidase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length507
- Mass (Da)55,969
- Last updated2022-12-14 v1
- MD5 ChecksumF42A0D267D71AB672307FBDCBA3BD8AC
Computationally mapped potential isoform sequences
There are 17 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
P12955 | PEPD_HUMAN | PEPD | 493 | ||
V9GYE4 | V9GYE4_HUMAN | PEPD | 55 | ||
V9GYL0 | V9GYL0_HUMAN | PEPD | 42 | ||
A0A8V8TN48 | A0A8V8TN48_HUMAN | PEPD | 361 | ||
A0A8V8TN70 | A0A8V8TN70_HUMAN | PEPD | 115 | ||
A0A8V8TNF2 | A0A8V8TNF2_HUMAN | PEPD | 478 | ||
A0A8V8TNH5 | A0A8V8TNH5_HUMAN | PEPD | 93 | ||
A0A8V8TLR6 | A0A8V8TLR6_HUMAN | PEPD | 195 | ||
A0A8V8TM81 | A0A8V8TM81_HUMAN | PEPD | 30 | ||
A0A8V8TM86 | A0A8V8TM86_HUMAN | PEPD | 133 | ||
A0A494C165 | A0A494C165_HUMAN | PEPD | 523 | ||
A0A494C194 | A0A494C194_HUMAN | PEPD | 224 | ||
A0A8V8TLL9 | A0A8V8TLL9_HUMAN | PEPD | 510 | ||
A0A8V8TLN7 | A0A8V8TLN7_HUMAN | PEPD | 386 | ||
A0A8V8TLP2 | A0A8V8TLP2_HUMAN | PEPD | 430 | ||
A0A8V8TLP4 | A0A8V8TLP4_HUMAN | PEPD | 495 | ||
K7ES25 | K7ES25_HUMAN | PEPD | 515 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC008744 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
AC010485 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
KF456560 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |