A0A8V1A097 · A0A8V1A097_CHICK
- ProteinHydroxyacid oxidase 2
- GeneHAO2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids366 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Catalytic activity
- 2-hydroxyoctanoate + O2 = 2-oxooctanoate + H2O2This reaction proceeds in the forward direction.
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 88-90 | FMN (UniProtKB | ChEBI) | ||||
Sequence: PTG | ||||||
Binding site | 117 | FMN (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 139 | FMN (UniProtKB | ChEBI) | ||||
Sequence: Q | ||||||
Binding site | 141 | glyoxylate (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 167 | glyoxylate (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 176 | glyoxylate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 237 | FMN (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 259 | FMN (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Active site | 261 | Proton acceptor | ||||
Sequence: H | ||||||
Binding site | 261 | glyoxylate (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 264 | glyoxylate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 292-296 | FMN (UniProtKB | ChEBI) | ||||
Sequence: DGGIR | ||||||
Binding site | 315-316 | FMN (UniProtKB | ChEBI) | ||||
Sequence: GR |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisome | |
Molecular Function | FMN binding | |
Molecular Function | oxidoreductase activity |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus
Accessions
- Primary accessionA0A8V1A097
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 9-366 | FMN hydroxy acid dehydrogenase | ||||
Sequence: LCAMAMVCLLDFEAYAEKYLPKIAWDFFAAGADECSTRDENILAYKRIRFRPRMLRDVSMLDTRTKILGTEISFPVGIAPTGFHQLAWPDGEKSTARAAKAMGTCYIASTYSTCSLEEIAAAAPGGFRWFQLYIHRNRAVSRQLVQQAEALGFQGLVLTADLPYTGKRRNDVRNGFRLPPHMKLKNLEGAFEGDDRSEYGLPPNSLDPSVTWDDIYWLRSLTHLPIVIKGILTKEDAELAVRHGVQGIIVSNHGGRQLDGAPATIDALVEVVEAVRDRVEVYLDGGIRKGSDVLKALALGAKCVFIGRPALWGLAYKGEEGLQDVLRILRDEFRLSMALAGCASISEIGQDLVQFSKL |
Sequence similarities
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length366
- Mass (Da)40,494
- Last updated2022-12-14 v1
- Checksum42E011C210464A69
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8V0ZYI3 | A0A8V0ZYI3_CHICK | HAO2 | 364 | ||
A0A8V0ZWE6 | A0A8V0ZWE6_CHICK | HAO2 | 355 | ||
A0A8V1A3V7 | A0A8V1A3V7_CHICK | HAO2 | 362 |
Keywords
- Technical term