A0A8V0YY16 · FOXI3_CHICK

  • Protein
    Forkhead box protein I3
  • Gene
    FOXI3
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Transcription factor required for pharyngeal arch development, which is involved in otic placode development.

Features

Showing features for dna binding.

139550100150200250300350
TypeIDPosition(s)Description
DNA binding131-225Fork-head

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Functionsequence-specific DNA binding
Biological Processotic placode development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Forkhead box protein I3

Gene names

    • Name
      FOXI3

Organism names

  • Taxonomic identifier
  • Strain
    • Red jungle fowl
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus

Accessions

  • Primary accession
    A0A8V0YY16

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004587551-395Forkhead box protein I3

Expression

Tissue specificity

Initially expressed in the pre-placodal ectoderm surrounding the neural plate, which will give rise to all craniofacial sensory organs (PubMed:23124078, PubMed:24780628).
Expression then becomes restricted to a region immediately anterior to the first pair of somites that will give rise to the otic and epibranchial placodes, before becoming down-regulated from this region and restricted to the ectoderm and endoderm of the pharyngeal arches (PubMed:23124078).

Structure

3D structure databases

Family & Domains

Features

Showing features for region, motif, compositional bias.

TypeIDPosition(s)Description
Region216-287Disordered
Motif221-227Nuclear localization signal
Compositional bias332-348Polar residues
Region332-366Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    395
  • Mass (Da)
    41,271
  • Last updated
    2022-12-14 v1
  • Checksum
    D1123E0BAF9955A2
MAVYCSENFSVYPQPSLHPPGAAAAAAAAAAAAAAAAASSGQRAGGYALGDYGAPANAGYLWGMNSPAPYLQGPPGSGAAASPFLPPASYGCSRGGQLVGSPSGPGSPSAGGAELSWLSLASQEELLKLVRPPYSYSALIAMAIQSAPERKLTLSHIYQYVAENFPFYKRSKAGWQNSIRHNLSLNDCFRKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSEPNTPATTAAASSLGGLKAEEERPIPASGKPCGNSPPPELDPSPSARDHPKSSSPSGIISSTPSCLSTFFSGMSSLSGGGSRLTGGLSTDLHHRNFSAGQLSGGTFTPSSSSSQEVPSPEQLQRVAGPSPAYYSSFHPSSGSQGAQYNHYYNFTVNSLIYTRDGTEV

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8V0Z4R3A0A8V0Z4R3_CHICKFOXI3382

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias332-348Polar residues

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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