A0A8T9KJA7 · A0A8T9KJA7_9BILA
- ProteinCytochrome c oxidase subunit 1
- GeneCOX1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids139 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- 4 Fe(II)-[cytochrome c] + 8 H+(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H+(out) + 2 H2OThis reaction proceeds in the forward direction.
4 RHEA-COMP:10350 + 8 H+ (in)CHEBI:15378+ CHEBI:15379 = 4 RHEA-COMP:14399 + 4 H+ (out)CHEBI:15378+ 2 CHEBI:15377
Cofactor
Pathway
Energy metabolism; oxidative phosphorylation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | mitochondrion | |
Molecular Function | cytochrome-c oxidase activity | |
Molecular Function | heme binding | |
Biological Process | aerobic respiration |
Names & Taxonomy
Protein names
- Recommended nameCytochrome c oxidase subunit 1
- Alternative names
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Enoplea > Dorylaimia > Trichinellida > Trichuridae > Trichuris
Accessions
- Primary accessionA0A8T9KJA7
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 39-56 | Helical | ||||
Sequence: IYAMMSIGILGCFVWGHH | ||||||
Transmembrane | 68-90 | Helical | ||||
Sequence: AYFTAATMIIGIPTGVKIFSWLA | ||||||
Transmembrane | 102-124 | Helical | ||||
Sequence: LMLWVSGFLVLFTMGGLTGVSLA |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-139 | Cytochrome oxidase subunit I profile | ||||
Sequence: WFFGHPEVYILVLPAFGTISESILYMAGKFKVFGPLGMIYAMMSIGILGCFVWGHHMYTIGMDVDTRAYFTAATMIIGIPTGVKIFSWLATLYGSASPSSPLMLWVSGFLVLFTMGGLTGVSLANASLDLLVHDTYYVV |
Sequence similarities
Belongs to the heme-copper respiratory oxidase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length139
- Mass (Da)15,166
- Last updated2022-10-12 v1
- Checksum324D408C80DDC114
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: W | ||||||
Non-terminal residue | 139 | |||||
Sequence: V |