A0A8T6ZM05 · A0A8T6ZM05_9BURK

  • Protein
    Thiol:disulfide interchange protein DsbD
  • Gene
    dsbD
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionelectron transfer activity
Molecular Functionprotein-disulfide reductase (NAD(P)H) activity
Biological Processcell redox homeostasis
Biological Processcytochrome complex assembly

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Thiol:disulfide interchange protein DsbD
  • EC number
  • Alternative names
    • Protein-disulfide reductase
      (Disulfide reductase
      )

Gene names

    • Name
      dsbD
    • ORF names
      NH14_029870

Organism names

  • Taxonomic identifier
  • Strain
    • LMG 19450
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia

Accessions

  • Primary accession
    A0A8T6ZM05

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane209-242Helical
Transmembrane254-278Helical
Transmembrane290-313Helical
Transmembrane334-364Helical
Transmembrane370-398Helical
Transmembrane410-428Helical
Transmembrane434-452Helical
Transmembrane464-485Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond138↔144Redox-active
Disulfide bond229↔351Redox-active
Disulfide bond551↔554Redox-active

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain506-634Thioredoxin
Region637-657Disordered
Compositional bias640-657Polar residues

Sequence similarities

Belongs to the thioredoxin family. DsbD subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    657
  • Mass (Da)
    68,378
  • Last updated
    2022-10-12 v1
  • Checksum
    CFB5F2E2206A7A81
MFKRFDRRSRAAPYTSFLAFFALVGCVLPLLFGAATARADDNFLPPDQAFTFSASEEPGVVDVHFKIADGYYMYRERFAFATRDGAATLGDAQIPPGHVKFDTTFNKNVETYRKEITIRVPVKQASGAFDLAVTSQGCADAGICYPPAEHVYHVSGPALQAAAGGQSMVGNGAPATPATPSASADDAQQPWYERATSADYAQSLLQGGGFFGVVGLYFLAGVVLSLLPCSYPMIPILSAIIVGEGAQVTRARGFALSFVYVLGMALVYTVLGIAAALVGQSLGAWLQNPWVLGVFAGLLTAFALMLIAGYDLALPQRWQDGASRASQGRSGGKFAAVAVMGALSALVAGACMTAPLFAVLAFIAHTGNAVLGGAALFAMGIGLGVPLMIIGLGAGTLLPRAGTWMDGVKVFFGIALLAAALWIVWPVLRASAQMLLAALWLLLAAAALGLFTPNAGASNVWRRLGRGVGAAFAIWAATLIVGLSAGSADPLRPLAVLAARTGGATGNGGAQTGAAEADALTFAPVRSSAQLDAMLKTAGKPSMLDFYADWCVSCKEMENLTFSDPRVQARLAQLGLLRADVTANNADDQALLKRFGLFGPPGIIFFDASGQEVLRVVGYENADKFLARLDRVVAQGQSPAPSAKPVQSVLSTLTGRS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias640-657Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JTDB02000013
EMBL· GenBank· DDBJ
NLP65270.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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