A0A8T6ZJJ8 · A0A8T6ZJJ8_9BURK
- ProteinGlucose-6-phosphate 1-dehydrogenase
- Genezwf
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids493 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
Catalytic activity
- D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH + H+
Pathway
Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 151 | NADP+ (UniProtKB | ChEBI) | |||
Binding site | 181 | substrate | |||
Binding site | 185 | substrate | |||
Binding site | 219 | substrate | |||
Binding site | 238 | substrate | |||
Active site | 243 | Proton acceptor | |||
Binding site | 343 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | glucose-6-phosphate dehydrogenase activity | |
Molecular Function | NADP binding | |
Biological Process | glucose metabolic process | |
Biological Process | pentose-phosphate shunt, oxidative branch |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlucose-6-phosphate 1-dehydrogenase
- EC number
- Short namesG6PD
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia
Accessions
- Primary accessionA0A8T6ZJJ8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 17-190 | Glucose-6-phosphate dehydrogenase NAD-binding | |||
Domain | 192-488 | Glucose-6-phosphate dehydrogenase C-terminal | |||
Sequence similarities
Belongs to the glucose-6-phosphate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length493
- Mass (Da)54,829
- Last updated2022-10-12 v1
- MD5 Checksum15AB3B643F7DE3F9EE82D680372D7BB5
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JTDB02000011 EMBL· GenBank· DDBJ | NLP64991.1 EMBL· GenBank· DDBJ | Genomic DNA |