A0A8T6ZJG7 · A0A8T6ZJG7_9BURK
- ProteinSulfate adenylyltransferase subunit 2
- GenecysD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids321 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
Catalytic activity
- sulfate + ATP + H+ = adenosine 5'-phosphosulfate + diphosphate
Pathway
Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | sulfate adenylyltransferase (ATP) activity | |
Biological Process | sulfate assimilation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSulfate adenylyltransferase subunit 2
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Paraburkholderia
Accessions
- Primary accessionA0A8T6ZJG7
Proteomes
Interaction
Subunit
Heterodimer composed of CysD, the smaller subunit, and CysN.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-23 | Disordered | |||
Compositional bias | 9-23 | Basic and acidic residues | |||
Domain | 48-275 | Phosphoadenosine phosphosulphate reductase | |||
Region | 299-321 | Disordered | |||
Sequence similarities
Belongs to the PAPS reductase family. CysD subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length321
- Mass (Da)37,210
- Last updated2022-10-12 v1
- MD5 ChecksumF6ABFC98AA20C27B04E215D7E7A0BD48
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 9-23 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JTDB02000010 EMBL· GenBank· DDBJ | NLP64858.1 EMBL· GenBank· DDBJ | Genomic DNA |