A0A8T6RI89 · A0A8T6RI89_9ARCH

Function

function

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for site.

TypeIDPosition(s)Description
Site489Determinant of potassium independence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    K(+)-insensitive pyrophosphate-energized proton pump
  • EC number
  • Alternative names
    • Membrane-bound proton-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (H(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      EAX96_05035

Organism names

Accessions

  • Primary accession
    A0A8T6RI89

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-28Helical
Transmembrane60-78Helical
Transmembrane90-113Helical
Transmembrane141-165Helical
Transmembrane171-190Helical
Transmembrane274-296Helical
Transmembrane317-336Helical
Transmembrane342-362Helical
Transmembrane396-420Helical
Transmembrane426-449Helical
Transmembrane494-512Helical
Transmembrane524-552Helical
Transmembrane600-619Helical
Transmembrane625-648Helical
Transmembrane701-720Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    722
  • Mass (Da)
    77,263
  • Last updated
    2022-10-12 v1
  • Checksum
    989D24B1B9D401C8
MTMTLSLVFLILGAIGGIISIGFAFYLWMMVKKLSTGEGETHNVYKAIREGAKAYIKREFKTIFAIAGILSIIIFFALDLKPWLSGLPSFVFLSFWIGTITSLAASFIGMDIATRTNVRVAIMAKQGLEPAMKTGFNGGTIMGMLVFGVNVIQIVITYLFLYMIFPGNYQAIVVNIVGCAFGGSFTSVIAQLGGGIYTKGADVGADIVGKIEQGIPEDDVRNPAVVADLVGDNVGDCAGRSADLYETLTSELISSMILGLSLFILPGSPLGDSVIFFPFLIRFIATIATIIGYFFVKQKKKIEAGETGPWKLLNTGLYLSSSIIAVIYVLLVLLIFQSVFLVFAAIFGIAANLIMGFIFEYFTSIDKKPVKTIIEASETGPATNIIQGMSNGLGSVFIPLSIIAMMILGAFGFGALFGVFSLSGRFILGGTYGIVIMSMGMTSGTGIILSMDGFGPIVDNAGGIAEMSGMGEDIRKNTDLLDATGNSTKSLTKGFSIISGTTIGFVTIFAYIELINSEMGITNAMINMGFVNVAVGGIFGVITVFLFVSLLMRSVGKTAHDMIEEVRRQFREIPGIMEWKEKPDYGRCVDISTISALKNMIFPALLIIIMPIAVGIFLGPFTLGAFLIIATFTGGAMGIFMNVSGASWDNAKKGRKHLQDKSNPETIKAYQAAVIGDTVGDPCKDTAGSSLGSFVTTINNLAITFFPLFVFTYGIALHFIGW

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RDOG01000003
EMBL· GenBank· DDBJ
NHI91844.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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