A0A8T6RGQ0 · A0A8T6RGQ0_THOAR
- ProteinK(+)-insensitive pyrophosphate-energized proton pump
- GenehppA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids713 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
Catalytic activity
- diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate
Cofactor
Features
Showing features for site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 474 | Determinant of potassium independence | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | diphosphate hydrolysis-driven proton transmembrane transporter activity | |
Molecular Function | inorganic diphosphate phosphatase activity | |
Molecular Function | magnesium ion binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameK(+)-insensitive pyrophosphate-energized proton pump
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Asgard group > Candidatus Thorarchaeota
Accessions
- Primary accessionA0A8T6RGQ0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 6-23 | Helical | ||||
Sequence: LSGLLAIFVALYTYQRIV | ||||||
Transmembrane | 53-74 | Helical | ||||
Sequence: ILMLFTIIVGAFIAVLFGQFGI | ||||||
Transmembrane | 80-99 | Helical | ||||
Sequence: YFLGSLASMAAGYIGVIVAT | ||||||
Transmembrane | 120-145 | Helical | ||||
Sequence: VAFRAGSVMGLMIAGIALVGLGSLYW | ||||||
Transmembrane | 165-183 | Helical | ||||
Sequence: LWEIITGFSFGASTVALFA | ||||||
Transmembrane | 265-287 | Helical | ||||
Sequence: LGLLPLMIAAIGTISSVLGVFLV | ||||||
Transmembrane | 299-319 | Helical | ||||
Sequence: LNRGTYFTTLLFVVFTVVVVI | ||||||
Transmembrane | 325-348 | Helical | ||||
Sequence: IIIAVSAIVGLIAGVFIAFTSDVF | ||||||
Transmembrane | 379-402 | Helical | ||||
Sequence: YSYGLLSVIPSVLGIATAMVVSFI | ||||||
Transmembrane | 479-497 | Helical | ||||
Sequence: GFAIGASAISVLALFAAFI | ||||||
Transmembrane | 517-541 | Helical | ||||
Sequence: ANPYVLAGALIGALVPVAFSAILIL | ||||||
Transmembrane | 588-608 | Helical | ||||
Sequence: LMPGTLVAILVTVTTGIILGI | ||||||
Transmembrane | 686-709 | Helical | ||||
Sequence: LLVVISLTAMLFLPVIARLNIWLI |
Keywords
- Cellular component
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Sequence similarities
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length713
- Mass (Da)74,659
- Last updated2022-10-12 v1
- ChecksumA10D786F645E7EC1