A0A8T6RGQ0 · A0A8T6RGQ0_THOAR

Function

function

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for site.

TypeIDPosition(s)Description
Site474Determinant of potassium independence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    K(+)-insensitive pyrophosphate-energized proton pump
  • EC number
  • Alternative names
    • Membrane-bound proton-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (H(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      EAX81_08340

Organism names

Accessions

  • Primary accession
    A0A8T6RGQ0

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-23Helical
Transmembrane53-74Helical
Transmembrane80-99Helical
Transmembrane120-145Helical
Transmembrane165-183Helical
Transmembrane265-287Helical
Transmembrane299-319Helical
Transmembrane325-348Helical
Transmembrane379-402Helical
Transmembrane479-497Helical
Transmembrane517-541Helical
Transmembrane588-608Helical
Transmembrane686-709Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    713
  • Mass (Da)
    74,659
  • Last updated
    2022-10-12 v1
  • Checksum
    A10D786F645E7EC1
MGTAILSGLLAIFVALYTYQRIVRADEGDERMREVSGLIEKGAYSFLKVQYRILMLFTIIVGAFIAVLFGQFGIPIAISYFLGSLASMAAGYIGVIVATKANRRTAAAAITGGLNPAFKVAFRAGSVMGLMIAGIALVGLGSLYWLWNFVLPDSLFTATPKEAELWEIITGFSFGASTVALFAKAGGGIYTKTADLSADLVGKIEHHIPEDDPRNPAAVADAVGDNVGDVAGTGADIYDSNVAAILAAAILGAGIDIHFTPVLPLGLLPLMIAAIGTISSVLGVFLVRPKEDQDPGPALNRGTYFTTLLFVVFTVVVVIVLNLSIIIAVSAIVGLIAGVFIAFTSDVFTSDRGLSTFKPVPRMVESAEKSAANLILSGYSYGLLSVIPSVLGIATAMVVSFILGSNLGYGEWEGGIYCVAIAAVGLLSTNGMIMSSDAYGPIVDNARGVIEQAQAPKEAIVACDKLDASGNTAKAITKGFAIGASAISVLALFAAFIESTGTLNIPGVVGLTDVNLANPYVLAGALIGALVPVAFSAILILGVERNSERMIEEIRRQFREYPGILEGTTKPDYDRCIAIATSGSIRELMPGTLVAILVTVTTGIILGIEALAGFLGGAVMAGLILALLMDNAGGAWDNTKKIIESPEYITYEKGTEDWHRVHDISVTGDMVGDPFKDTAGPAINTLLVVISLTAMLFLPVIARLNIWLIGLFW

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
RDOC01000015
EMBL· GenBank· DDBJ
NHI84293.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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