Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A8T4H4N9 · A0A8T4H4N9_9SPHI

Function

function

Catalyzes the ferrous insertion into protoporphyrin IX.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site195Fe2+ (UniProtKB | ChEBI)
Binding site298Fe2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionferrochelatase activity
Molecular Functionmetal ion binding
Biological Processheme biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ferrochelatase
  • EC number
  • Alternative names
    • Heme synthase
    • Protoheme ferro-lyase

Gene names

    • Name
      hemH
    • ORF names
      J5U18_00875

Organism names

  • Taxonomic identifier
  • Strain
    • WQ 2009
  • Taxonomic lineage
    Bacteria > Bacteroidota > Sphingobacteriia > Sphingobacteriales > Sphingobacteriaceae > Rhinopithecimicrobium

Accessions

  • Primary accession
    A0A8T4H4N9

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the ferrochelatase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    344
  • Mass (Da)
    38,919
  • Last updated
    2022-10-12 v1
  • MD5 Checksum
    93E26E4705B27AE63F05380ACC3FE021
MKKKATKGILLVQLGTPDSPSTKDVRKYLTEFLMDGRVIDIPYLNRTLLVKGIIAPTRAPKSAKVYESIWDKETGSPLMYYSKLQKDALQEALGEDYHVELAMRYQNPSIELALSKMEGMLLDSIRVIPMFPQYASATSGSIIDRVMELIRKWQYFPALSFVNSFCEDELLIEVIADHAKQHDLAEYDHYLFSYHGLPVRQLGKIDPTGQLKCPENGCEQCKVQTNSYCYVSQCYATSRAIVKKLNLPEGSYSTCFQSRLGKEPWIQPYTSVALKELAESGKKKLLVFSPAFVADCIETIDEIAVEYAAEFKELGGEKVQLVESLNNDPKWIESLRRLAVDAKN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAGKSB010000001
EMBL· GenBank· DDBJ
MBP3942130.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help