A0A8T3W433 · A0A8T3W433_UNCTM
- ProteinDNA-directed RNA polymerase subunit Rpo1N
- Generpo1N
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids938 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Catalytic activity
- RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate
Cofactor
Protein has several cofactor binding sites:
Note: Binds at least 2 Zn2+ per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 61 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 64 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 71 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 74 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 101 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 104 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 151 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 154 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 465 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 467 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 469 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | DNA-directed RNA polymerase complex | |
Molecular Function | DNA binding | |
Molecular Function | DNA-directed 5'-3' RNA polymerase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | zinc ion binding | |
Biological Process | DNA-templated transcription |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA-directed RNA polymerase subunit Rpo1N
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Candidatus Thermoplasmatota > Thermoplasmata
Accessions
- Primary accessionA0A8T3W433
Proteomes
Subcellular Location
Interaction
Subunit
Part of the RNA polymerase complex.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length938
- Mass (Da)104,583
- Last updated2022-10-12 v1
- ChecksumB8735DE658648A86
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
SUTB01000004 EMBL· GenBank· DDBJ | MBE6519196.1 EMBL· GenBank· DDBJ | Genomic DNA |