A0A8T3W433 · A0A8T3W433_UNCTM

  • Protein
    DNA-directed RNA polymerase subunit Rpo1N
  • Gene
    rpo1N
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds at least 2 Zn2+ per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site61Zn2+ 1 (UniProtKB | ChEBI)
Binding site64Zn2+ 1 (UniProtKB | ChEBI)
Binding site71Zn2+ 1 (UniProtKB | ChEBI)
Binding site74Zn2+ 1 (UniProtKB | ChEBI)
Binding site101Zn2+ 2 (UniProtKB | ChEBI)
Binding site104Zn2+ 2 (UniProtKB | ChEBI)
Binding site151Zn2+ 2 (UniProtKB | ChEBI)
Binding site154Zn2+ 2 (UniProtKB | ChEBI)
Binding site465Mg2+ (UniProtKB | ChEBI)
Binding site467Mg2+ (UniProtKB | ChEBI)
Binding site469Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionmagnesium ion binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit Rpo1N
  • EC number
  • Alternative names
    • DNA-directed RNA polymerase subunit A'

Gene names

    • Name
      rpo1N
    • Synonyms
      rpoA1
    • ORF names
      E7Z70_06665

Organism names

Accessions

  • Primary accession
    A0A8T3W433

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Part of the RNA polymerase complex.

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain208-519RNA polymerase N-terminal
Region917-938Disordered

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    938
  • Mass (Da)
    104,583
  • Last updated
    2022-10-12 v1
  • Checksum
    B8735DE658648A86
MTYGITKRIGSIKFSCLSPEEIRKMSAIKVITPDTYNDEGYPYPGGLMDPHMGVIEPGIRCKTCGCKVDECPGHFGHIELALPVIHVGFIKDIKMLLESTCCKCGRLMLSEEQIKDRMDSMEKMEELGGGTIEKKLFTKDTAKDASGKTVCPYCNETQIKIKLDKPTTFREVEDNHKLTPKEVRERLERISDDDLKALGIDPETCRPEWMVLTVLAVPPVSVRPSITLEAGDKSEDDLTHKLVDVLRINQRLRENRDAGAPQLIVEDLWELLQYHVTTYFDNQTSGIPPARHRSGRPLKTLEQRLKGKEGRFRSNLSGKRVNFSARTVISPDPLLSINDVGVPTFAARELTVPLRVNQYNIEKVREIVRRGPMEDQLNFPYVPGANYVIRSDGRKIRVTERNAAEVAEGLDIGYTVERQLVDGDVVLFNRQPSLHRMSMMAHRVKVMEGKTFRFNLCVCPPYNADFDGDEMNLHVLQSDEARAEARIIMQVQENILSPRYGGPIIGAIHDHITGAYFLTHNNPRFNAEEAANIMFKLPEVPLPEPMVDEETGEKYWTGKQLFSTILPKDFNTSFRANICNCTNQAECKKGNCPNDGYVIIRNGELVCGTIDVKAIGNSKGKILDRIARDYGSERAALFINQVTRLALGALMNHGFSTGISDEDIPKEASLQINNNTQECIDKVTALVDSYRSGTLQQMPGRSLRETLEVSVMQVLGKARDDAGTIAGKYLGMDNPAVIMAKAGARGSMLNLSQMAGCVGQQAVRGERLARGYWDRTLSHFEKGDLGAYARGFCSNSYKSGLTPTEFFFHAMGGREGLVDTAVRTSRSGYMQRRLVSALEDLKLTSDGTVRNTVGTVIQFKYGEDGVDPAKTVRGKAIDLDDLFFEVFGDEAENFNQEVEKDVGGDYGSLEKDEMEYIEEEGDGEDMDDLDLDYDGGGE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
SUTB01000004
EMBL· GenBank· DDBJ
MBE6519196.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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